Impaired Working Memory Updating for Emotional Stimuli in Depressed Patients
文献类型：期刊论文
| 作者 | Zhang, Dandan1,2; Xie, Hui2; He, Zhenhong2; Wei, Zhaoguo3; Gu, Ruolei1,4
|
| 刊名 | FRONTIERS IN BEHAVIORAL NEUROSCIENCE
 |
| 出版日期 | 2018-04-04 |
| 卷号 | 12期号:0页码:65 |
| 关键词 | depression working memory emotion updating N-back task |
| ISSN号 | 1662-5153 |
| DOI | 10.3389/fnbeh.2018.00065 |
| 产权排序 | 1 |
| 文献子类 | Article |
| 英文摘要 | Although two previous studies have demonstrated that depressed individuals showed deficits in working memory (WM) updating of both negative and positive contents, the effects were confounded by shifting dysfunctions and the detailed neural mechanism associated with the failure in N-back task is not clear. Using a 2-back task, the current study examined the WM updating of positive, negative and neutral contents in depressed patients. It is found that depressed patients performed poorer than healthy controls only when updating positive material. Using event-related potential (ERP) technique, the current study also investigated the neural correlates of updating deficits in depression. According to previous studies, the n-back task was divided into three sub-processes, i.e., encoding, matching and maintaining. Our ERP results showed that depressed patients had smaller occipital P1 for positive material compared to healthy controls, indicating their insensitivity to positive items on early encoding stage. Besides, depressed patients had larger frontal P2 and parietal late positive potential (LPP) than healthy controls irrespective of the valence of the words, reflecting that patients are inefficient during matching (P2) and maintaining (LPP) processes. These two mechanisms (insufficient attention to positive stimuli and low efficiency in matching and maintaining) together lead to the deficits of WM updating in depression. |
| WOS关键词 | EVENT-RELATED POTENTIALS ; N-BACK TASK ; CARD SORTING TEST ; MAJOR DEPRESSION ; SELECTIVE ATTENTION ; UNIPOLAR DEPRESSION ; COGNITIVE IMPAIRMENT ; CLINICAL DEPRESSION ; EXECUTIVE FUNCTIONS ; BRAIN POTENTIALS |
| WOS研究方向 | Behavioral Sciences ; Neurosciences & Neurology |
| 语种 | 英语 |
| WOS记录号 | WOS:000429279500001 |
| 资助机构 | National Natural Science Foundation of China(31571120) ; National Key Basic Research Program of China (973 Program)(2014CB744600) ; Training Program for Excellent Young College Faculty in Guangdong(YQ2015143) ; Shenzhen Basic Research Project(JCYJ20170302143246158) ; Project for Young Faculty of Humanities and Social Sciences in Shenzhen University(17QNFC43) |
| 源URL | [http://ir.psych.ac.cn/handle/311026/25741]  |
| 专题 | 心理研究所_社会与工程心理学研究室 |
| 通讯作者 | Gu, Ruolei |
| 作者单位 | 1.Inst Psychol, CAS Key Lab Behav Sci, Beijing, Peoples R China 2.Shenzhen Univ, Shenzhen Key Lab Affect & Social Cognit Sci, Shenzhen, Peoples R China 3.Shenzhen Kangning Hosp, Dept Clin Psychol, Shenzhen, Peoples R China 4.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Dandan,Xie, Hui,He, Zhenhong,et al. Impaired Working Memory Updating for Emotional Stimuli in Depressed Patients[J]. FRONTIERS IN BEHAVIORAL NEUROSCIENCE,2018,12(0):65. |
| APA | Zhang, Dandan,Xie, Hui,He, Zhenhong,Wei, Zhaoguo,&Gu, Ruolei.(2018).Impaired Working Memory Updating for Emotional Stimuli in Depressed Patients.FRONTIERS IN BEHAVIORAL NEUROSCIENCE,12(0),65. |
| MLA | Zhang, Dandan,et al."Impaired Working Memory Updating for Emotional Stimuli in Depressed Patients".FRONTIERS IN BEHAVIORAL NEUROSCIENCE 12.0(2018):65. |
入库方式： OAI收割
来源：心理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。