A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation
文献类型：期刊论文
| 作者 | Tianming Song; Xia Liu; Yawei Qu; Haixiao Liu ; Chengpeng Bao; Chengcai Leng; Zhenhua Hu; Kun Wang; Jie Tian
|
| 刊名 | Molecular Imaging
 |
| 出版日期 | 2015-08 |
| 卷号 | 14期号:8页码:7290 |
| 关键词 | Endoscopic Cerenkov Luminescence Imaging System |
| 英文摘要 | Cerenkov luminescence imaging is an emerging optical technique for imaging the distribution of radiopharmaceuticals in vivo. However, because of the light scattering effect, it cannot obtain optical information from deep internal organs. To overcome this challenge, we established a novel endoscopic Cerenkov luminescence imaging system that used a clinically approved laparoscope and an electronmultiplying charge-coupled device camera. We assessed the performance of the system through a series of in vitro and in vivo experiments. The results demonstrated superior superficial imaging resolution (0.1 mm), a large field of view (500 mm2 with 10 mm imaging distance), and superb imaging sensitivity (imaging 1 μCi) of our system. It captured the weak Cerenkov signal from internal organs successfully and was applied to intraoperative surgical navigation of tumor resection. It offered objective information of the tumor location and tumor residual during the surgical operation. This technique holds great potential for clinical translation. |
| WOS记录号 | WOS:000365597500002 |
| 源URL | [http://ir.ia.ac.cn/handle/173211/11997]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 通讯作者 | Zhenhua Hu |
| 推荐引用方式 GB/T 7714 | Tianming Song,Xia Liu,Yawei Qu,et al. A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation[J]. Molecular Imaging,2015,14(8):7290. |
| APA | Tianming Song.,Xia Liu.,Yawei Qu.,Haixiao Liu.,Chengpeng Bao.,...&Jie Tian.(2015).A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation.Molecular Imaging,14(8),7290. |
| MLA | Tianming Song,et al."A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation".Molecular Imaging 14.8(2015):7290. |
入库方式： OAI收割
来源：自动化研究所
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