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Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction

文献类型：期刊论文

作者Jiang, Shixin1; Liu, Jie1; An, Yu1; Zhang, Guanglei1; Ye, Jinzuo2; Mao, Yamin2; He, Kunshan2; Chi, Chongwei2,3; Tian, Jie2,3
刊名BIOMEDICAL OPTICS EXPRESS
出版日期2016-06-01
卷号7期号:6页码:2342-2359
关键词Image Reconstruction Techniques Spectroscopy Fluorescence And Luminescence Tomography
DOI10.1364/BOE.7.002342
文献子类Article
英文摘要Fluorescence molecular tomography (FMT) is a promising tomographic method in preclinical research, which enables noninvasive real-time three-dimensional (3-D) visualization for in vivo studies. The ill-posedness of the FMT reconstruction problem is one of the many challenges in the studies of FMT. In this paper, we propose a l(2,1)-norm optimization method using a priori information, mainly the structured sparsity of the fluorescent regions for FMT reconstruction. Compared to standard sparsity methods, the structured sparsity methods are often superior in reconstruction accuracy since the structured sparsity utilizes correlations or structures of the reconstructed image. To solve the problem effectively, the Nesterov's method was used to accelerate the computation. To evaluate the performance of the proposed l(2,1)-norm method, numerical phantom experiments and in vivo mouse experiments are conducted. The results show that the proposed method not only achieves accurate and desirable fluorescent source reconstruction, but also demonstrates enhanced robustness to noise. (C) 2016 Optical Society of America
WOS关键词DIFFUSE OPTICAL TOMOGRAPHY ; ELEMENT BASED TOMOGRAPHY ; IMAGE-RECONSTRUCTION ; BIOLUMINESCENCE TOMOGRAPHY ; SPARSITY REGULARIZATION ; ALGORITHM ; LIGHT ; INFORMATION ; MICROSCOPY ; TISSUE
WOS研究方向Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
语种英语
WOS记录号WOS:000377514000023
资助机构National Natural Science Foundation of China(81571836 ; Fundamental Research Funds for the Central Universities(2015JBM026) ; China Postdoctoral Science Foundation(2015M570032 ; Beijing Natural Science Foundation(7164270 ; Open Research Project from SKLMCCS(20150103) ; 81227901 ; 2015T80155) ; 20140491524) ; 61231004 ; 61501462)
源URL[http://ir.ia.ac.cn/handle/173211/12187]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者Liu, Jie
作者单位1.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Dept Biomed Engn, 3 Shangyuancun, Beijing 100044, Peoples R China
2.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
3.Chinese Acad Sci, Inst Automat, Beijing Key Lab Mol Imaging, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714		 Jiang, Shixin,Liu, Jie,An, Yu,et al. Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction[J]. BIOMEDICAL OPTICS EXPRESS,2016,7(6):2342-2359.
APA Jiang, Shixin.,Liu, Jie.,An, Yu.,Zhang, Guanglei.,Ye, Jinzuo.,...&Tian, Jie.(2016).Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction.BIOMEDICAL OPTICS EXPRESS,7(6),2342-2359.
MLA Jiang, Shixin,et al."Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction".BIOMEDICAL OPTICS EXPRESS 7.6(2016):2342-2359.

入库方式： OAI收割

来源：自动化研究所

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