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In vivo pentamodal tomographic imaging for small animals

文献类型：期刊论文

作者Liu, Muhan1,2,3; Guo, Hongbo3,4; Liu, Hongbo1,2,3; Zhang, Zeyu3; Chi, Chongwei3; Hui, Hui3; Dong, Di3; Hu, Zhenhua3,5; Tian, Jie1,2,3,5
刊名BIOMEDICAL OPTICS EXPRESS
出版日期2017-03-01
卷号8期号:3页码:1356-1371
关键词Pentamodal Tomographic Imaging
DOI10.1364/BOE.8.001356
文献子类Article
英文摘要Multimodality molecular imaging emerges as a powerful strategy for correlating multimodal information. We developed a pentamodal imaging system which can perform positron emission tomography, bioluminescence tomography, fluorescence molecular tomography, Cerenkov luminescence tomography and X-ray computed tomography successively. Performance of sub-systems corresponding to different modalities were characterized. In vivo multimodal imaging of an orthotopic hepatocellular carcinoma xenograft mouse model was performed, and acquired multimodal images were fused. The feasibility of pentamodal tomographic imaging system was successfully validated with the imaging application on the mouse model. The ability of integrating anatomical, metabolic, and pharmacokinetic information promises applications of multimodality molecular imaging in precise medicine. (C) 2017 Optical Society of America.
WOS关键词BIOLUMINESCENCE TOMOGRAPHY ; CLINICAL-APPLICATIONS ; MRI ; DEVICES ; SYSTEM ; RECONSTRUCTION ; MODALITIES ; ALGORITHM ; SPECT/CT ; PLATFORM
WOS研究方向Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
语种英语
WOS记录号WOS:000395942600007
资助机构National Natural Science Foundation of China (NSFC)(81227901 ; National Key Research and Development Program of China(2016YFC0102600) ; 81527805 ; 61231004 ; 61622117 ; 81671759)
源URL[http://ir.ia.ac.cn/handle/173211/14427]  
专题自动化研究所_中国科学院分子影像重点实验室
作者单位1.Xidian Univ, Engn Res Ctr Mol & Neuro Imaging, Minist Educ, Xian 710071, Shaanxi, Peoples R China
2.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China
3.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging, Beijing 100190, Peoples R China
4.Northwest Univ Xian, Sch Informat Sci & Technol, Xian 710069, Peoples R China
5.Chinese Acad Sci, Inst Automat, State Key Lab Management & Control Complex Syst, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714		 Liu, Muhan,Guo, Hongbo,Liu, Hongbo,et al. In vivo pentamodal tomographic imaging for small animals[J]. BIOMEDICAL OPTICS EXPRESS,2017,8(3):1356-1371.
APA Liu, Muhan.,Guo, Hongbo.,Liu, Hongbo.,Zhang, Zeyu.,Chi, Chongwei.,...&Tian, Jie.(2017).In vivo pentamodal tomographic imaging for small animals.BIOMEDICAL OPTICS EXPRESS,8(3),1356-1371.
MLA Liu, Muhan,et al."In vivo pentamodal tomographic imaging for small animals".BIOMEDICAL OPTICS EXPRESS 8.3(2017):1356-1371.

入库方式： OAI收割

来源：自动化研究所

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