Recent advances in high-performance fluorescent and bioluminescent RNA imaging probes
文献类型：期刊论文
| 作者 | Xia, Yuqiong1; Zhang, Ruili1; Wang, Zhongliang1; Tian, Jie1,2 ; Chen, Xiaoyuan3
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| 刊名 | CHEMICAL SOCIETY REVIEWS
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| 出版日期 | 2017-05-21 |
| 卷号 | 46期号:10页码:2824-2843 |
| DOI | 10.1039/c6cs00675b |
| 文献子类 | Review |
| 英文摘要 | RNA plays an important role in life processes. Imaging of messenger RNAs (mRNAs) and micro-RNAs (miRNAs) not only allows us to learn the formation and transcription of mRNAs and the biogenesis of miRNAs involved in various life processes, but also helps in detecting cancer. High-performance RNA imaging probes greatly expand our view of life processes and enhance the cancer detection accuracy. In this review, we summarize the state-of-the-art high-performance RNA imaging probes, including exogenous probes that can image RNA sequences with special modification and endogeneous probes that can directly image endogenous RNAs without special treatment. For each probe, we review its structure and imaging principle in detail. Finally, we summarize the application of mRNA and miRNA imaging probes in studying life processes as well as in detecting cancer. By correlating the structures and principles of various probes with their practical uses, we compare different RNA imaging probes and offer guidance for better utilization of the current imaging probes and the future design of higher-performance RNA imaging probes. |
| WOS关键词 | IN-SITU HYBRIDIZATION ; ENHANCED-RAMAN-SPECTROSCOPY ; ROLLING CIRCLE AMPLIFICATION ; MULTIPLE MESSENGER-RNAS ; LIVING BACTERIAL-CELLS ; DNA MOLECULAR BEACONS ; LIVE CELLS ; GENE-EXPRESSION ; GOLD NANOPARTICLES ; MICRORNA BIOGENESIS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000401905400008 |
| 资助机构 | National Natural Science Foundation of China(81671753 ; national 1000 Young Talents Program of China ; Fundamental Research Funds for the Central universities(JB161202) ; Intramural Research Program, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH) ; 81501524) |
| 源URL | [http://ir.ia.ac.cn/handle/173211/15114]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Xidian Univ, Sch Life Sci & Technol, Engn Res Ctr Mol Imaging & Neuroimaging, Minist Educ, Xian 710126, Shaanxi, Peoples R China 2.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 3.NIBIB, Lab Mol Imaging & Nanomed LOMIN, NIH, Bethesda, MD 20892 USA |
| 推荐引用方式 GB/T 7714 | Xia, Yuqiong,Zhang, Ruili,Wang, Zhongliang,et al. Recent advances in high-performance fluorescent and bioluminescent RNA imaging probes[J]. CHEMICAL SOCIETY REVIEWS,2017,46(10):2824-2843. |
| APA | Xia, Yuqiong,Zhang, Ruili,Wang, Zhongliang,Tian, Jie,&Chen, Xiaoyuan.(2017).Recent advances in high-performance fluorescent and bioluminescent RNA imaging probes.CHEMICAL SOCIETY REVIEWS,46(10),2824-2843. |
| MLA | Xia, Yuqiong,et al."Recent advances in high-performance fluorescent and bioluminescent RNA imaging probes".CHEMICAL SOCIETY REVIEWS 46.10(2017):2824-2843. |
入库方式： OAI收割
来源：自动化研究所
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