Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome
文献类型：期刊论文
| 作者 | Lin, Yusong1,2; Bai, Yan3,4,5,6; Liu, Peng7; Yang, Xuejuan7; Qin, Wei7; Gu, Jianqin4,8; Ding, Degang4,9; Tian, Jie10 ; Wang, Meiyun3,4,5,6,8
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| 刊名 | PLOS ONE
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| 出版日期 | 2017-09-19 |
| 卷号 | 12期号:9 |
| DOI | 10.1371/journal.pone.0184896 |
| 文献子类 | Article |
| 英文摘要 | The purpose of this study was to explore the neural mechanism in Chronic prostatitis/Chronic pelvic pain syndrome (CP/CPPS) using resting-state functional magnetic resonance imaging. The functional magnetic resonance imaging was performed on 31 male CP/CPPS-patients and 31 age and education matched male healthy controls on a 3-T magnetic resonance imaging unit. A two-sample t-test was adopted to reveal the regional homogeneity between the patients and healthy controls. The mean regional homogeneity values in the alerted brain regions of patients were correlated with the clinical measurements by using Pearson's correlation analyses. The CP/CPPS-patients had significantly decreased regional homogeneity in the bilateral anterior cingulate cortices, insular cortices and right medial prefrontal cortex, while significantly increased regional homogeneity in the brainstem and right thalamus compared with the healthy controls. In the CP/CPPSpatients, the mean regional homogeneity value in the left anterior cingulate cortex, bilateral insular cortices and brainstem were respectively correlated with the National Institutes of Health Chronic Prostatitis Symptom Index total score and pain subscale. These brain regions are important in the pain modulation process. Therefore, an impaired pain modulatory system, either by decreased descending pain inhibition or enhanced pain facilitation, may explain the pain symptoms in CP/CPPS. |
| WOS关键词 | OPIOID RECEPTOR AVAILABILITY ; ANTERIOR CINGULATE CORTEX ; NATIONAL-INSTITUTES ; SYMPTOM INDEX ; BACK-PAIN ; FIBROMYALGIA ; FMRI ; HEALTH ; UNPLEASANTNESS ; ACTIVATION |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000411166600050 |
| 资助机构 | National Natural Science Foundation of China(31470047 ; Henan Province Scientific and Technological Innovation Talents Project(164200510014) ; Henan Province Scientific and Technological Cooperation Project(152106000014) ; Key Project of Henan Medical Science and Technology Project(201501011) ; 81641168 ; 81271565 ; 81601466 ; 81271644 ; 81471811) |
| 源URL | [http://ir.ia.ac.cn/handle/173211/20734]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Zhengzhou Univ, Cooperat Innovat Ctr Internet Healthcare, Zhengzhou, Henan, Peoples R China 2.Zhengzhou Univ, Sch Software & Appl Technol, Zhengzhou, Henan, Peoples R China 3.Zhengzhou Univ, Peoples Hosp, Dept Radiol, Zhengzhou, Henan, Peoples R China 4.Henan Prov Peoples Hosp, Zhengzhou, Henan, Peoples R China 5.Henan Key Lab Med Imaging Neurol Dis, Xinjiang, Peoples R China 6.Henan Univ, Med Sch, Zhengzhou, Henan, Peoples R China 7.Xidian Univ, Sch Life Sci & Technol, Xian, Shaanxi, Peoples R China 8.Zhengzhou Univ, Peoples Hosp, Henan Prov Clin Big Data Anal & Serv Engn Res Ctr, Zhengzhou, Henan, Peoples R China 9.Zhengzhou Univ, Peoples Hosp, Dept Urol, Zhengzhou, Henan, Peoples R China 10.Chinese Acad Sci, Inst Automat, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Yusong,Bai, Yan,Liu, Peng,et al. Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome[J]. PLOS ONE,2017,12(9). |
| APA | Lin, Yusong.,Bai, Yan.,Liu, Peng.,Yang, Xuejuan.,Qin, Wei.,...&Wang, Meiyun.(2017).Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome.PLOS ONE,12(9). |
| MLA | Lin, Yusong,et al."Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome".PLOS ONE 12.9(2017). |
入库方式： OAI收割
来源：自动化研究所
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