Tumour-homing chimeric polypeptide-conjugated polypyrrole nanoparticles for imaging-guided synergistic photothermal and chemical therapy of cancer
文献类型：期刊论文
| 作者 | Sun, Mengmeng1; Guo, Jianwen1; Hao, Hanjun1; Tong, Tong2 ; Wang, Kun2; Gao, Weiping1
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| 刊名 | THERANOSTICS
 |
| 出版日期 | 2018 |
| 卷号 | 8期号:10页码:2634-2645 |
| 关键词 | Tumour Targeting Nanomedicine Polypyrrole Photothermal Therapy Combination Therapy |
| DOI | 10.7150/thno.24705 |
| 文献子类 | Article |
| 英文摘要 | Near-infrared (NIR)-absorbing conjugated polymer nanoparticles are interesting for imaging-guided combination therapy, especially for synergistic photothermal therapy and chemotherapy; however, most of them target tumours passively through the enhanced permeability and retention (EPR) effect, leading to low utilization efficiency. To address this problem, we report an active tumour-targeting strategy of tumour-homing chimeric polypeptide-conjugated NIR-absorbing conjugated-polymer nanoparticles as a new class of drug nanocarriers for imaging-guided combination therapy of cancer. |
| WOS关键词 | IN-VIVO ; DOXORUBICIN CONJUGATE ; DRUG CARRIER ; POLYMERS ; DELIVERY ; AGENTS ; CELLS |
| WOS研究方向 | Research & Experimental Medicine |
| 语种 | 英语 |
| WOS记录号 | WOS:000429878500003 |
| 资助机构 | National Natural Science Foundation of China(21534006) ; Beijing Natural Science Foundation(2172028) |
| 源URL | [http://ir.ia.ac.cn/handle/173211/22015]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 作者单位 | 1.Tsinghua Univ, Sch Med, Dept Biomed Engn, Beijing 100084, Peoples R China 2.Chinese Acad Sci, Inst Automat, State Key Lab Management & Control Complex Syst, Key Lab Mol Imaging, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Mengmeng,Guo, Jianwen,Hao, Hanjun,et al. Tumour-homing chimeric polypeptide-conjugated polypyrrole nanoparticles for imaging-guided synergistic photothermal and chemical therapy of cancer[J]. THERANOSTICS,2018,8(10):2634-2645. |
| APA | Sun, Mengmeng,Guo, Jianwen,Hao, Hanjun,Tong, Tong,Wang, Kun,&Gao, Weiping.(2018).Tumour-homing chimeric polypeptide-conjugated polypyrrole nanoparticles for imaging-guided synergistic photothermal and chemical therapy of cancer.THERANOSTICS,8(10),2634-2645. |
| MLA | Sun, Mengmeng,et al."Tumour-homing chimeric polypeptide-conjugated polypyrrole nanoparticles for imaging-guided synergistic photothermal and chemical therapy of cancer".THERANOSTICS 8.10(2018):2634-2645. |
入库方式： OAI收割
来源：自动化研究所
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