An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images
文献类型:期刊论文
作者 | Xie, Qiwei1,2,3![]() ![]() ![]() |
刊名 | BIODATA MINING
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出版日期 | 2017-12-20 |
卷号 | 10期号:10页码:40 |
关键词 | In Vivo Two-photon imagIng Synapse Bouton Spine Image Enhancement |
DOI | 10.1186/s13040-017-0161-5 |
文献子类 | Article |
英文摘要 | Background: In the nervous system, the neurons communicate through synapses. The size, morphology, and connectivity of these synapses are significant in determining the functional properties of the neural network. Therefore, they have always been a major focus of neuroscience research. Two-photon laser scanning microscopy allows the visualization of synaptic structures in vivo, leading to many important findings. However, the identification and quantification of structural imaging data currently rely heavily on manual annotation, a method that is both time-consuming and prone to bias. |
WOS关键词 | DENDRITIC SPINES ; SEGMENTATION ; PLASTICITY |
WOS研究方向 | Mathematical & Computational Biology |
语种 | 英语 |
WOS记录号 | WOS:000418806400001 |
资助机构 | Special Program of Beijing Municipal Science & Technology Commission(Z161100000216146) ; Science and Technology Development Fund of Macau(044/2015/A2) ; Chinese Academy of Sciences(YZ201671) ; CAS(XDB02060001) ; Institute of Automation, CAS(Y3J2031DZ1) ; National Natural Science Foundation of China(61673381 ; 61201050 ; 61306070 ; 31472001) |
源URL | [http://ir.ia.ac.cn/handle/173211/21725] ![]() |
专题 | 类脑智能研究中心_微观重建与智能分析 |
作者单位 | 1.Res Base Beijing Modern Mfg Dev, 100 Pingleyuan, Beijing 100124, Peoples R China 2.Beijing Univ Technol, Sch Management, Data Min Lab, 100 Pingleyuan, Beijing 100124, Peoples R China 3.Chinese Acad Sci, Inst Automat, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China 4.Macau Univ Sci & Technol, Fac Informat Technol, Ave Wai Long, Taipa, Macau, Peoples R China 5.Chinese Acad Sci, Inst Neurosci, 320 Yue Yang Rd, Shanghai 200031, Peoples R China 6.Beijing Normal Univ, 19 Waida Jie, Beijing 100875, Peoples R China 7.Chinese Acad Sci, Shanghai Inst Biol Sci, Ctr Excellence Brain Sci & Intelligence Technol, 320 Yue Yang Rd, Shanghai 200031, Peoples R China 8.Univ Chinese Acad Sci, Sch Future Technol, 19A Yuquan Rd, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Xie, Qiwei,Chen, Xi,Deng, Hao,et al. An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images[J]. BIODATA MINING,2017,10(10):40. |
APA | Xie, Qiwei.,Chen, Xi.,Deng, Hao.,Liu, Danqian.,Sun, Yingyu.,...&Han, Hua.(2017).An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images.BIODATA MINING,10(10),40. |
MLA | Xie, Qiwei,et al."An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images".BIODATA MINING 10.10(2017):40. |
入库方式: OAI收割
来源:自动化研究所
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