Bayesian Analysis of Folding and Unfolding Time Series of Single-Forced RNAs
文献类型：期刊论文
| 作者 | Ou-Yang, Zhong-can ; Xue, Xiao Chuan; Tong, Huan; Liu, Fei; Liu, F , Tsinghua Univ, Ctr Adv Study, Beijing 100084, Peoples R China
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| 刊名 | JOURNAL OF PHYSICAL CHEMISTRY B
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| 出版日期 | 2008 |
| 卷号 | 112期号:44页码:13680-13683 |
| ISSN号 | 1520-6106 |
| 关键词 | Optical Tweezers Kinetics Models Dna |
| 英文摘要 | On the basis of a coarse-grain physical model of the folding and unfolding of single-forced RNAs conducted in light tweezer experiments, we theoretically investigate the feasibility of inferring the RNA's intrinsic kinetic parameters from the noisy time series of the molecule's extension. A Bayesian approach using Monte Carlo Markov Chain is proposed. We prove that this statistical approach is efficient and accurate in inferring the molecule's physical parameters, even if the experimental data are yielded under a narrow range of forces. |
| 学科主题 | Physics |
| URL标识 | 查看原文 |
| WOS记录号 | WOS:000260533100003 |
| 公开日期 | 2012-08-02 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/5440]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 通讯作者 | Liu, F , Tsinghua Univ, Ctr Adv Study, Beijing 100084, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ou-Yang, Zhong-can,Xue, Xiao Chuan,Tong, Huan,et al. Bayesian Analysis of Folding and Unfolding Time Series of Single-Forced RNAs[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2008,112(44):13680-13683. |
| APA | Ou-Yang, Zhong-can,Xue, Xiao Chuan,Tong, Huan,Liu, Fei,&Liu, F , Tsinghua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.(2008).Bayesian Analysis of Folding and Unfolding Time Series of Single-Forced RNAs.JOURNAL OF PHYSICAL CHEMISTRY B,112(44),13680-13683. |
| MLA | Ou-Yang, Zhong-can,et al."Bayesian Analysis of Folding and Unfolding Time Series of Single-Forced RNAs".JOURNAL OF PHYSICAL CHEMISTRY B 112.44(2008):13680-13683. |
入库方式： OAI收割
来源：理论物理研究所
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