Theory of DNA melting based on the Peyrard-Bishop model
文献类型：期刊论文
| 作者 | Zhang, YL; Zheng, WM ; Liu, JX; Chen, YZ; Zhang, YL , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
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| 刊名 | PHYSICAL REVIEW E
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| 出版日期 | 1997 |
| 卷号 | 56期号:6页码:7100-7115 |
| 关键词 | Statistical-mechanics Nonlinear Model Thermal-denaturation Phase-transition Dynamics |
| ISSN号 | 1063-651X |
| 英文摘要 | The DNA melting based on the Peyrard-Bishop (PB) model is systematically investigated. Our study on the eigenvalues and eigenvectors of the transfer integral equation for the original PB model points out that the eigenvectors are composed of two kinds: discrete bound states that constitute the internal states of a DNA molecule and the continuous unbound states that represent its dissociated states. Another process controlling the melting of DNA-the dissociation equilibrium between duplex and single-stranded DNAs-is introduced, which leads to an extended model applicable for a realistic DNA chain with a finite number of base pairs. Based on the expansion of kernels, the calculations of the thermodynamic quantities of the system are reduced to multiplication of matrix series. Calculations on model block DNAs show the method is much more efficient than molecular dynamic simulation and has enough high precision to handle the melting of a natural DNA with arbitrary sequence. The discreteness effect and nonlinear effect of the model are discussed based on the Gaussian model. Rigorous melting curves for periodic DNA with two and three base pairs in a unit cell and boundary effects are presented by the transfer integral approach. |
| 学科主题 | Physics |
| URL标识 | 查看原文 |
| WOS记录号 | WOS:000071043500107 |
| 公开日期 | 2012-08-29 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/12403]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 通讯作者 | Zhang, YL , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Zhang, YL,Zheng, WM,Liu, JX,et al. Theory of DNA melting based on the Peyrard-Bishop model[J]. PHYSICAL REVIEW E,1997,56(6):7100-7115. |
| APA | Zhang, YL,Zheng, WM,Liu, JX,Chen, YZ,&Zhang, YL , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China..(1997).Theory of DNA melting based on the Peyrard-Bishop model.PHYSICAL REVIEW E,56(6),7100-7115. |
| MLA | Zhang, YL,et al."Theory of DNA melting based on the Peyrard-Bishop model".PHYSICAL REVIEW E 56.6(1997):7100-7115. |
入库方式： OAI收割
来源：理论物理研究所
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