Statistically significant strings are related to regulatory elements in the promoter regions of Saccharomyces cerevisiae
文献类型：期刊论文
| 作者 | Hu, R; Wang, B; Hu, R , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 10080, Peoples R China. |
| 刊名 | PHYSICA A
 |
| 出版日期 | 2001 |
| 卷号 | 290期号:40972页码:464-474 |
| 关键词 | Dna-sequences Nucleotide-sequences Genome Genes |
| ISSN号 | 0378-4371 |
| 英文摘要 | Finding out statistically significant words in DNA and protein sequences forms the basis for many genetic studies. By applying the maximal entropy principle, we give one systematic way to study the nonrandom occurrence of words in DNA or protein sequences. Through comparison with experimental results, it was shown that patterns of regulatory binding sites in Saccharomyces cerevisiae (yeast) genomes tend to occur significantly in the promoter regions. We studied two correlated gene families of yeast. The method successfully extracts the binding sites verified by experiments in each family. Many putative regulatory sites in the upstream regions are proposed. The study also suggested that some regulatory sites are active in both directions, while others show directional preference. (C) 2001 Elsevier Science B.V. All rights reserved. |
| 学科主题 | Physics |
| URL标识 | 查看原文 |
| WOS记录号 | WOS:000166891700011 |
| 公开日期 | 2012-08-29 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/12814]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 通讯作者 | Hu, R , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 10080, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Hu, R,Wang, B,Hu, R , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 10080, Peoples R China.. Statistically significant strings are related to regulatory elements in the promoter regions of Saccharomyces cerevisiae[J]. PHYSICA A,2001,290(40972):464-474. |
| APA | Hu, R,Wang, B,&Hu, R , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 10080, Peoples R China..(2001).Statistically significant strings are related to regulatory elements in the promoter regions of Saccharomyces cerevisiae.PHYSICA A,290(40972),464-474. |
| MLA | Hu, R,et al."Statistically significant strings are related to regulatory elements in the promoter regions of Saccharomyces cerevisiae".PHYSICA A 290.40972(2001):464-474. |
入库方式： OAI收割
来源：理论物理研究所
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