The elastic theory of a single DNA molecule
文献类型：期刊论文
| 作者 | Zhou, HJ ; Zhang, Y; Ou-Yang, ZC; Zhou, HJ , Chinese Acad Sci, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
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| 刊名 | PRAMANA-JOURNAL OF PHYSICS
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| 出版日期 | 2003 |
| 卷号 | 61期号:2页码:353-360 |
| 关键词 | Double-stranded Dna Supercoiled Dna Polymerase Mechanics |
| ISSN号 | 0304-4289 |
| 英文摘要 | We study the elastic responses of double- (ds) and single-stranded (ss) DNA at external force fields. A double-strand-polymer elastic model is constructed and solved by path integral methods and Monte Carlo simulations to understand the entropic elasticity, cooperative extensibility, and supercoiling property of dsDNA. The good agreement with experiments indicates that short-ranged base-pair stacking interaction is crucial for the stability and the high deformability of dsDNA. Hairpin-coil transition in ssDNA is studied with generating function method. A threshold force is needed to pull the ssDNA hairpin patterns, stabilized by base pairing and base-pair stacking, into random coils. This phase transition is predicted to be of first order for stacking potential higher than some critical level, in accordance with experimental observations. |
| 学科主题 | Physics |
| URL标识 | 查看原文 |
| 公开日期 | 2012-08-29 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/13254]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 通讯作者 | Zhou, HJ , Chinese Acad Sci, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Zhou, HJ,Zhang, Y,Ou-Yang, ZC,et al. The elastic theory of a single DNA molecule[J]. PRAMANA-JOURNAL OF PHYSICS,2003,61(2):353-360. |
| APA | Zhou, HJ,Zhang, Y,Ou-Yang, ZC,&Zhou, HJ , Chinese Acad Sci, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China..(2003).The elastic theory of a single DNA molecule.PRAMANA-JOURNAL OF PHYSICS,61(2),353-360. |
| MLA | Zhou, HJ,et al."The elastic theory of a single DNA molecule".PRAMANA-JOURNAL OF PHYSICS 61.2(2003):353-360. |
入库方式： OAI收割
来源：理论物理研究所
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