In-phase implies large likelihood for independent codon model: distinguishing coding from non-coding sequences
文献类型：期刊论文
| 作者 | Zheng, WM ; Wu, F; Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.
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| 刊名 | JOURNAL OF THEORETICAL BIOLOGY
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| 出版日期 | 2003 |
| 卷号 | 223期号:2页码:199-203 |
| 关键词 | Identification Regions |
| ISSN号 | 0022-5193 |
| 英文摘要 | It is proven that under the independent codon model, the likelihood of a DNA coding sequence read according to the correct frame is asymptotically larger than that read with an incorrect frame. Based on this proposition, a single set of probabilities of the codon usage is enough for discriminating the six frames of coding sequences under the independent codon model. The direct coding sequence of Escherichia coli genome is taken as an example to examine the codon independency by using the mutual information and chi(2) analysis. The contrast between the coding frame and the two offset frames is evident. A self-learning approach for generating training set is proposed to estimate probability parameters. (C) 2003 Elsevier Rience Ltd. All rights reserved. |
| 学科主题 | Physics |
| URL标识 | 查看原文 |
| WOS记录号 | WOS:000184078400006 |
| 公开日期 | 2012-08-29 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/13257]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 通讯作者 | Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Zheng, WM,Wu, F,Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China.. In-phase implies large likelihood for independent codon model: distinguishing coding from non-coding sequences[J]. JOURNAL OF THEORETICAL BIOLOGY,2003,223(2):199-203. |
| APA | Zheng, WM,Wu, F,&Zheng, WM , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China..(2003).In-phase implies large likelihood for independent codon model: distinguishing coding from non-coding sequences.JOURNAL OF THEORETICAL BIOLOGY,223(2),199-203. |
| MLA | Zheng, WM,et al."In-phase implies large likelihood for independent codon model: distinguishing coding from non-coding sequences".JOURNAL OF THEORETICAL BIOLOGY 223.2(2003):199-203. |
入库方式： OAI收割
来源：理论物理研究所
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