Secondary-structure-favored hydrophobic-polar lattice model of protein folding
文献类型：期刊论文
| 作者 | Chen, H; Zhou, X; Ou-Yang, ZC ; Chen, H , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.
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| 刊名 | PHYSICAL REVIEW E
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| 出版日期 | 2001 |
| 卷号 | 64期号:4页码:- |
| 关键词 | Packing Density Cooperativity Superfamilies Designability Polymers Origins Chains |
| ISSN号 | 1063-651X |
| 英文摘要 | Protein folding studied using a two-dimensional lattice model with the Hamiltonian including both hydrophobic interactions and main chain hydrogen bond interactions of amino acids. Since compact conformations have different designabilities and only highly designable conformations can act as native structural candidates [H. Li, R. Helling, C. Tang, and N. Wingreen, Science 273, 666 (1996)], it is shown that hydrophobic interaction alone is insufficient to explain the appearance of a high proportion of regular secondary structures, especially beta sheets whose content decreases with increasing designability, but interactions of main chain hydrogen bonds can account for this. Thus the emergence of only a small number of structure types (folds) among all possible structures can be understood to some extent. |
| 学科主题 | Physics |
| WOS记录号 | WOS:000171649000052 |
| 公开日期 | 2012-08-29 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/13659]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 通讯作者 | Chen, H , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Chen, H,Zhou, X,Ou-Yang, ZC,et al. Secondary-structure-favored hydrophobic-polar lattice model of protein folding[J]. PHYSICAL REVIEW E,2001,64(4):-. |
| APA | Chen, H,Zhou, X,Ou-Yang, ZC,&Chen, H , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China..(2001).Secondary-structure-favored hydrophobic-polar lattice model of protein folding.PHYSICAL REVIEW E,64(4),-. |
| MLA | Chen, H,et al."Secondary-structure-favored hydrophobic-polar lattice model of protein folding".PHYSICAL REVIEW E 64.4(2001):-. |
入库方式： OAI收割
来源：理论物理研究所
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