Unfolding single RNA molecules by mechanical force: A stochastic kinetic method
文献类型：期刊论文
| 作者 | Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.; Liu, F; Ou-Yang, ZC
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| 刊名 | PHYSICAL REVIEW E
 |
| 出版日期 | 2004 |
| 卷号 | 70期号:4页码:- |
| 关键词 | Titin Immunoglobulin Domains Secondary Structure Stranded-dna Protein Elasticity Simulation Algorithm Dynamics Models |
| ISSN号 | 1539-3755 |
| 英文摘要 | Using simple polymer elastic theory and known RNA free energies, we study the single RNA folding and unfolding on the secondary structure level under mechanical constant force by stochastic kinetic simulation. As a primary application, this method is used to simulate the experiment performed by Liphardt et al. [Science 292, 733 (2001)]. The extension-force curves in equilibrium and kinetic reaction rate constants for folding and unfolding are calculated. Our results show that the agreement between simulation and experimental measurements is satisfactory. |
| 学科主题 | Physics |
| URL标识 | 查看原文 |
| WOS记录号 | WOS:000225689500006 |
| 公开日期 | 2012-08-30 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/13995]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 通讯作者 | Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.,Liu, F,Ou-Yang, ZC. Unfolding single RNA molecules by mechanical force: A stochastic kinetic method[J]. PHYSICAL REVIEW E,2004,70(4):-. |
| APA | Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.,Liu, F,&Ou-Yang, ZC.(2004).Unfolding single RNA molecules by mechanical force: A stochastic kinetic method.PHYSICAL REVIEW E,70(4),-. |
| MLA | Liu, F , Tsing Hua Univ, Ctr Adv Study, Beijing 100084, Peoples R China.,et al."Unfolding single RNA molecules by mechanical force: A stochastic kinetic method".PHYSICAL REVIEW E 70.4(2004):-. |
入库方式： OAI收割
来源：理论物理研究所
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