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Whole proteome prokaryote phylogeny without sequence alignment: A K-string composition approach
文献类型：期刊论文
| 作者 | Qi, J; Wang, B; Hao, BI; Qi, J , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China. |
| 刊名 | JOURNAL OF MOLECULAR EVOLUTION
 |
| 出版日期 | 2004 |
| 卷号 | 58期号:1页码:1-11 |
| 关键词 | Universal Tree Life Archaeal |
| ISSN号 | 0022-2844 |
| 英文摘要 | A systematic way of inferring evolutionary relatedness of microbial organisms from the oligopeptide content, i.e., frequency of amino acid K-strings in their complete proteomes, is proposed. The new method circumvents the ambiguity of choosing the genes for phylogenetic reconstruction and avoids the necessity of aligning sequences of essentially different length and gene content. The only "parameter" in the method is the length K of the oligopeptides, which serves to tune the "resolution power" of the method. The topology of the trees converges with K increasing. Applied to a total of 109 organisms, including 16 Archaea, 87 Bacteria, and 6 Eukarya, it yields an unrooted tree that agrees with the biologists' "tree of life" based on SSU rRNA comparison in a majority of basic branchings, and especially, in all lower taxa. |
| 学科主题 | Physics |
| URL标识 | 查看原文 |
| WOS记录号 | WOS:000188112200001 |
| 公开日期 | 2012-08-30 |
| 源URL | [http://ir.itp.ac.cn/handle/311006/14146]  |
| 专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
| 通讯作者 | Qi, J , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Qi, J,Wang, B,Hao, BI,et al. Whole proteome prokaryote phylogeny without sequence alignment: A K-string composition approach[J]. JOURNAL OF MOLECULAR EVOLUTION,2004,58(1):1-11. |
| APA | Qi, J,Wang, B,Hao, BI,&Qi, J , Acad Sinica, Inst Theoret Phys, POB 2735, Beijing 100080, Peoples R China..(2004).Whole proteome prokaryote phylogeny without sequence alignment: A K-string composition approach.JOURNAL OF MOLECULAR EVOLUTION,58(1),1-11. |
| MLA | Qi, J,et al."Whole proteome prokaryote phylogeny without sequence alignment: A K-string composition approach".JOURNAL OF MOLECULAR EVOLUTION 58.1(2004):1-11. |
入库方式： OAI收割
来源：理论物理研究所
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