Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent
文献类型：期刊论文
| 作者 | Huang, H; Li J(李娟) ; Cui RL(崔荣丽); Chang YN(常亚男); Guo XH(郭喜红); Gu WH(古伟宏); Huang H(黄换); Chen K(陈奎); Lin GM(林国明); Dong JQ(董金泉)
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| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2016 |
| 卷号 | 6期号:63页码:58028-58033 |
| DOI | 10.1039/c6ra06733f |
| 通讯作者 | 邢更妹 ; 孙宝云 |
| 英文摘要 | Water-soluble GO-Gd@C-82 nanohybrids exhibit high relaxivities and could be explored as potential magnetic resonance imaging (MRI) contrast agents. To better understand the relaxation mechanism in the novel carbon nanohybrids, in the present paper, after layers of in-depth analysis and exploration, we propose that the structure and the physicochemical properties of the carbon nanohybrids contribute significantly to the enhanced relaxivity. Better electron transfer from Gd@C-82 to the GO nanosheet, appropriate electric conductivity and size of the GO used, an increased number of H proton exchange sites and an adequate concentration of Gd3+ should result in optimal equilibrium for high relaxivity of the GO-Gd@C-82. These results are important for constructing and optimizing novel nanoscale architectures with higher relaxivity. |
| 语种 | 英语 |
| WOS记录号 | WOS:000378725800031 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/260293]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Huang, H,Li J,Cui RL,et al. Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent[J]. RSC ADVANCES,2016,6(63):58028-58033. |
| APA | Huang, H.,李娟.,崔荣丽.,常亚男.,郭喜红.,...&Sun, BY.(2016).Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent.RSC ADVANCES,6(63),58028-58033. |
| MLA | Huang, H,et al."Adaption of the structure of carbon nanohybrids toward high-relaxivity for a new MRI contrast agent".RSC ADVANCES 6.63(2016):58028-58033. |
入库方式： OAI收割
来源：高能物理研究所
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