Bioaccumulation, Depuration, and Transfer to Offspring of C-13-Labeled Fullerenols by Daphnia magna
文献类型：期刊论文
| 作者 | Du, MM; Zhang, H; Li JX(李佳昕); Chang XL(常雪灵) ; Li, JX; Yan, CZ; Zhang, X; Chang, XL
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| 刊名 | ENVIRONMENTAL SCIENCE & TECHNOLOGY
 |
| 出版日期 | 2016 |
| 卷号 | 50期号:19页码:10421-10427 |
| DOI | 10.1021/acs.est.6b02596 |
| 通讯作者 | 常雪灵 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Fullerenols have wide application in the field of life sciences as a result of their extensive biocompatibility and biofunctionality. However, their environmental fate and ecotoxicological risks are largely unknown. In this study, stable isotope (C-13) labeling was applied to investigate the bioaccumulation and depuration of fullerenols in Daphnia magna. By incorporation of C-13 on the skeleton of fullerenols, the concentrations of fullerenols in the samples could be precisely determined on the basis of carbon isotope ratios (C-13/C-12). After exposure to C-13-labeled fullerenols in artificial freshwater for 48 h, the steady concentrations of fullerenols in D. magna were nearly 0.39 and 1.37% of the dry body weight in the 0.1 and 1.0 mg/L exposure groups, respectively. After 48 h of :depuration; D: magna could excrete 97.34 and 89.56% of the accumulated fullerenols in 0.1 and 1.0 mg/L exposure group, respectively. The depuration of fullerenols from D. magna followed first-order kinetics. Moreover, accumulated fullerenols in gravid D. magna could be transferred to the next generation of neonates. The results in present study demonstrated that,stable isotope (C-13) labeling is a powerful tool to investigate the,environmental fate and the potential impacts of fullerenols in ecological systems. |
| WOS关键词 | IN-VIVO ; C-60 ; NANOMATERIALS ; RATS ; CYTOTOXICITY ; EXPOSURE ; NC(60) ; CANCER ; MODEL ; WATER |
| 语种 | 英语 |
| WOS记录号 | WOS:000384841900015 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/260346]  |
| 专题 | 中国科学院高能物理研究所 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Du, MM,Zhang, H,Li JX,et al. Bioaccumulation, Depuration, and Transfer to Offspring of C-13-Labeled Fullerenols by Daphnia magna[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2016,50(19):10421-10427. |
| APA | Du, MM.,Zhang, H.,李佳昕.,常雪灵.,Li, JX.,...&Chang, XL.(2016).Bioaccumulation, Depuration, and Transfer to Offspring of C-13-Labeled Fullerenols by Daphnia magna.ENVIRONMENTAL SCIENCE & TECHNOLOGY,50(19),10421-10427. |
| MLA | Du, MM,et al."Bioaccumulation, Depuration, and Transfer to Offspring of C-13-Labeled Fullerenols by Daphnia magna".ENVIRONMENTAL SCIENCE & TECHNOLOGY 50.19(2016):10421-10427. |
入库方式： OAI收割
来源：高能物理研究所
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