DNA-Based Nanopore Sensing
文献类型：期刊论文
| 作者 | Liu, L; Wu, HC; Wu HC(吴海臣) ; Liu L(刘蕾)
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| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2016 |
| 卷号 | 55期号:49页码:15216-15222 |
| 关键词 | current signatures DNA probes nanopores quantification sensing |
| DOI | 10.1002/anie.201604405 |
| 通讯作者 | 吴海臣 |
| 英文摘要 | Nanopore sensing is an attractive, label-free approach that can measure single molecules. Although initially proposed for rapid and low-cost DNA sequencing, nanopore sensors have been successfully employed in the detection of a wide variety of substrates. Early successes were mostly achieved based on two main strategies by 1)creating sensing elements inside the nanopore through protein mutation and chemical modification or 2)using molecular adapters to enhance analyte recognition. Over the past fiveyears, DNA molecules started to be used as probes for sensing rather than substrates for sequencing. In this Minireview, we highlight the recent research efforts of nanopore sensing based on DNA-mediated characteristic current events. As nanopore sensing is becoming increasingly important in biochemical and biophysical studies, DNA-based sensing may find wider applications in investigating DNA-involving biological processes. |
| 语种 | 英语 |
| WOS记录号 | WOS:000389224000004 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/260456]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Liu, L,Wu, HC,Wu HC,et al. DNA-Based Nanopore Sensing[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2016,55(49):15216-15222. |
| APA | Liu, L,Wu, HC,吴海臣,&刘蕾.(2016).DNA-Based Nanopore Sensing.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,55(49),15216-15222. |
| MLA | Liu, L,et al."DNA-Based Nanopore Sensing".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55.49(2016):15216-15222. |
入库方式： OAI收割
来源：高能物理研究所
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