Single-pulse enhanced coherent diffraction imaging of bacteria with an X-ray free-electron laser
文献类型：期刊论文
| 作者 | Sun, ZB; Jiang, HD; Earnest, T; Gao, XY; Chai, ZF; Zhao, YL; Fan, CH; Ishikawa, T; Yabashi, M; Tono, K |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2016 |
| 卷号 | 6 |
| DOI | 10.1038/srep34008 |
| 通讯作者 | 高学云 |
| 英文摘要 | High-resolution imaging offers one of the most promising approaches for exploring and understanding the structure and function of biomaterials and biological systems. X-ray free-electron lasers (XFELs) combined with coherent diffraction imaging can theoretically provide high-resolution spatial information regarding biological materials using a single XFEL pulse. Currently, the application of this method suffers from the low scattering cross-section of biomaterials and X-ray damage to the sample. However, XFELs can provide pulses of such short duration that the data can be collected using the "diffract and destroy" approach before the effects of radiation damage on the data become significant. These experiments combine the use of enhanced coherent diffraction imaging with single-shot XFEL radiation to investigate the cellular architecture of Staphylococcus aureus with and without labeling by gold (Au) nanoclusters. The resolution of the images reconstructed from these diffraction patterns were twice as high or more for gold-labeled samples, demonstrating that this enhancement method provides a promising approach for the high-resolution imaging of biomaterials and biological systems. |
| 语种 | 英语 |
| WOS记录号 | WOS:000384045500001 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/261071]  |
| 专题 | 高能物理研究所_院士 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Sun, ZB,Jiang, HD,Earnest, T,et al. Single-pulse enhanced coherent diffraction imaging of bacteria with an X-ray free-electron laser[J]. SCIENTIFIC REPORTS,2016,6. |
| APA | Sun, ZB.,Jiang, HD.,Earnest, T.,Gao, XY.,Chai, ZF.,...&王亚玲.(2016).Single-pulse enhanced coherent diffraction imaging of bacteria with an X-ray free-electron laser.SCIENTIFIC REPORTS,6. |
| MLA | Sun, ZB,et al."Single-pulse enhanced coherent diffraction imaging of bacteria with an X-ray free-electron laser".SCIENTIFIC REPORTS 6(2016). |
入库方式： OAI收割
来源：高能物理研究所
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