A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions
文献类型：期刊论文
| 作者 | Gao QuanQuan1; Ren TingGe2 |
| 刊名 | SCIENCE CHINA-INFORMATION SCIENCES
 |
| 出版日期 | 2010-10-01 |
| 卷号 | 53期号:10页码:2047-2061 |
| 关键词 | intelligent calculation mathematical modeling measuring method efficacies of prescriptions |
| ISSN号 | 1674-733X |
| DOI | 10.1007/s11432-010-4068-8 |
| 英文摘要 | It is important to translate dosage of each medical herb in a prescription into intensity of its effects measured by mathematical models. In this paper, we present intelligent calculational algorithms on efficacies of prescriptions of Chinese Medicine (CM), study "how curative effects of any herb depend on dosage" when constructing CM intelligent systems, and discuss relevant issues and definitions. In order to measure intensities of effects of all herbs reasonably, the natural classification method is proposed to classify herbs into 38 natural classes according to their dosage ranges using the knowledge of CM dosage and distribution rules of herbs. Then the 38 natural classes are clustered to 6 basic classes reflecting characteristic attributes of various herbs. Based on the results of classified herbs, a set of nonlinear measuring functions of intensities of effects is designed for various basic classes. These functions have been embedded in our intelligent calculation system of efficacies of prescriptions. The effects of 560 herbs and curative efficacies of more than 1000 prescriptions derived from "ShangHan Lun", "JinGui YaoLue", "Ming Jia Yi An", etc., have been calculated and discovered successfully. It is proved that the accuracy of theses results by these models has been obviously enhanced. |
| 资助项目 | National Natural Science Foundation of China[60672141] ; National Key Technology R&D Program of China[2007BAI10B06] |
| WOS研究方向 | Computer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000281670000012 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/9593]  |
| 专题 | 中国科学院数学与系统科学研究院 |
| 通讯作者 | Gao QuanQuan |
| 作者单位 | 1.Chinese Acad Sci, Acad Math & Syst, Beijing 100190, Peoples R China 2.Beijing Univ Chinese Med, Beijing 100029, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao QuanQuan,Ren TingGe. A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions[J]. SCIENCE CHINA-INFORMATION SCIENCES,2010,53(10):2047-2061. |
| APA | Gao QuanQuan,&Ren TingGe.(2010).A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions.SCIENCE CHINA-INFORMATION SCIENCES,53(10),2047-2061. |
| MLA | Gao QuanQuan,et al."A measuring method of effects of herbs based on classification used for intelligent calculation of efficacies of prescriptions".SCIENCE CHINA-INFORMATION SCIENCES 53.10(2010):2047-2061. |
入库方式： OAI收割
来源：数学与系统科学研究院
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