中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Identifiability of models for clinical trials with noncompliance

文献类型:期刊论文

作者Xie, TF; Zhang, ZZ
刊名DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B
出版日期2004-08-01
卷号4期号:3页码:805-811
关键词asymptotic normality clinical trial compliance EV model instrumental variable
ISSN号1531-3492
英文摘要In this article we focus on clinical trials in which the compliance is measured with random errors, and develop an error-in-variables model for the analysis of the clinical trials. With this model, we separate the efficacy of prescribed treatment from that of the compliance. With additional information correlated with compliance, we prove that the model is identifiable, and get estimators for the parameters of interest, including the parameter reflecting the efficacy of the treatment. Furthermore, we extend the model to stratified populations, and discuss the asymptotic properties of the estimators.
WOS研究方向Mathematics
语种英语
WOS记录号WOS:000221965100034
出版者AMER INST MATHEMATICAL SCIENCES
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/19576]  
专题中国科学院数学与系统科学研究院
通讯作者Xie, TF
作者单位1.Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100081, Peoples R China
2.Beijing Univ Technol, Dept Appl Math, Beijing 100022, Peoples R China
推荐引用方式
GB/T 7714
Xie, TF,Zhang, ZZ. Identifiability of models for clinical trials with noncompliance[J]. DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B,2004,4(3):805-811.
APA Xie, TF,&Zhang, ZZ.(2004).Identifiability of models for clinical trials with noncompliance.DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B,4(3),805-811.
MLA Xie, TF,et al."Identifiability of models for clinical trials with noncompliance".DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B 4.3(2004):805-811.

入库方式: OAI收割

来源:数学与系统科学研究院

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