Semiparametric Transformation Models with Time-Varying Coefficients for Recurrent and Terminal Events
文献类型:期刊论文
作者 | Zhao, Xingqiu1; Zhou, Jie2; Sun, Liuquan2![]() |
刊名 | BIOMETRICS
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出版日期 | 2011-06-01 |
卷号 | 67期号:2页码:404-414 |
关键词 | Counting process Estimating equation Marginal model Model checking Recurrent events Terminal event Time-varying coefficients |
ISSN号 | 0006-341X |
DOI | 10.1111/j.1541-0420.2010.01458.x |
英文摘要 | In this article, we propose a family of semiparametric transformation models with time-varying coefficients for recurrent event data in the presence of a terminal event such as death. The new model offers great flexibility in formulating the effects of covariates on the mean functions of the recurrent events among survivors at a given time. For the inference on the proposed models, a class of estimating equations is developed and asymptotic properties of the resulting estimators are established. In addition, a lack-of-fit test is provided for assessing the adequacy of the model, and some tests are presented for investigating whether or not covariate effects vary with time. The finite-sample behavior of the proposed methods is examined through Monte Carlo simulation studies, and an application to a bladder cancer study is also illustrated. |
资助项目 | AMSS-PolyU Joint Research Institute ; Research Grant Council of Hong Kong ; National Natural Science Foundation of China[10731010] ; National Natural Science Foundation of China[10971015] ; National Natural Science Foundation of China[10721101] ; National Basic Research Program of China (973 Program)[2007CB814902] ; Key Laboratory of RCSDS, CAS[2008DP173182] |
WOS研究方向 | Life Sciences & Biomedicine - Other Topics ; Mathematical & Computational Biology ; Mathematics |
语种 | 英语 |
WOS记录号 | WOS:000292504000008 |
出版者 | WILEY-BLACKWELL |
源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/11580] ![]() |
专题 | 应用数学研究所 |
通讯作者 | Zhao, Xingqiu |
作者单位 | 1.Hong Kong Polytech Univ, Dept Appl Math, Hong Kong, Hong Kong, Peoples R China 2.Chinese Acad Sci, Inst Appl Math, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Zhao, Xingqiu,Zhou, Jie,Sun, Liuquan. Semiparametric Transformation Models with Time-Varying Coefficients for Recurrent and Terminal Events[J]. BIOMETRICS,2011,67(2):404-414. |
APA | Zhao, Xingqiu,Zhou, Jie,&Sun, Liuquan.(2011).Semiparametric Transformation Models with Time-Varying Coefficients for Recurrent and Terminal Events.BIOMETRICS,67(2),404-414. |
MLA | Zhao, Xingqiu,et al."Semiparametric Transformation Models with Time-Varying Coefficients for Recurrent and Terminal Events".BIOMETRICS 67.2(2011):404-414. |
入库方式: OAI收割
来源:数学与系统科学研究院
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