中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Semiparametric Transformation Models with Time-Varying Coefficients for Recurrent and Terminal Events

文献类型:期刊论文

作者Zhao, Xingqiu1; Zhou, Jie2; Sun, Liuquan2
刊名BIOMETRICS
出版日期2011-06-01
卷号67期号:2页码:404-414
关键词Counting process Estimating equation Marginal model Model checking Recurrent events Terminal event Time-varying coefficients
ISSN号0006-341X
DOI10.1111/j.1541-0420.2010.01458.x
英文摘要In this article, we propose a family of semiparametric transformation models with time-varying coefficients for recurrent event data in the presence of a terminal event such as death. The new model offers great flexibility in formulating the effects of covariates on the mean functions of the recurrent events among survivors at a given time. For the inference on the proposed models, a class of estimating equations is developed and asymptotic properties of the resulting estimators are established. In addition, a lack-of-fit test is provided for assessing the adequacy of the model, and some tests are presented for investigating whether or not covariate effects vary with time. The finite-sample behavior of the proposed methods is examined through Monte Carlo simulation studies, and an application to a bladder cancer study is also illustrated.
资助项目AMSS-PolyU Joint Research Institute ; Research Grant Council of Hong Kong ; National Natural Science Foundation of China[10731010] ; National Natural Science Foundation of China[10971015] ; National Natural Science Foundation of China[10721101] ; National Basic Research Program of China (973 Program)[2007CB814902] ; Key Laboratory of RCSDS, CAS[2008DP173182]
WOS研究方向Life Sciences & Biomedicine - Other Topics ; Mathematical & Computational Biology ; Mathematics
语种英语
WOS记录号WOS:000292504000008
出版者WILEY-BLACKWELL
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/11580]  
专题应用数学研究所
通讯作者Zhao, Xingqiu
作者单位1.Hong Kong Polytech Univ, Dept Appl Math, Hong Kong, Hong Kong, Peoples R China
2.Chinese Acad Sci, Inst Appl Math, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Xingqiu,Zhou, Jie,Sun, Liuquan. Semiparametric Transformation Models with Time-Varying Coefficients for Recurrent and Terminal Events[J]. BIOMETRICS,2011,67(2):404-414.
APA Zhao, Xingqiu,Zhou, Jie,&Sun, Liuquan.(2011).Semiparametric Transformation Models with Time-Varying Coefficients for Recurrent and Terminal Events.BIOMETRICS,67(2),404-414.
MLA Zhao, Xingqiu,et al."Semiparametric Transformation Models with Time-Varying Coefficients for Recurrent and Terminal Events".BIOMETRICS 67.2(2011):404-414.

入库方式: OAI收割

来源:数学与系统科学研究院

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