中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 数学与系统科学研究院
  3. 中国科学院数学与系统科学研究院
  4. 应用数学研究所
Additive mixed effect model for recurrent gap time data

文献类型：期刊论文

作者Ding, Jieli1; Sun, Liuquan2
刊名LIFETIME DATA ANALYSIS
出版日期2017-04-01
卷号23期号:2页码:223-253
关键词Additive mixed effect model Estimating equation Gap times Random effects Recurrent event data
ISSN号1380-7870
DOI10.1007/s10985-015-9341-0
英文摘要Gap times between recurrent events are often of primary interest in medical and observational studies. The additive hazards model, focusing on risk differences rather than risk ratios, has been widely used in practice. However, the marginal additive hazards model does not take the dependence among gap times into account. In this paper, we propose an additive mixed effect model to analyze gap time data, and the proposed model includes a subject-specific random effect to account for the dependence among the gap times. Estimating equation approaches are developed for parameter estimation, and the asymptotic properties of the resulting estimators are established. In addition, some graphical and numerical procedures are presented for model checking. The finite sample behavior of the proposed methods is evaluated through simulation studies, and an application to a data set from a clinic study on chronic granulomatous disease is provided.
资助项目National Natural Science Foundation of China[11231010] ; National Natural Science Foundation of China[11101314] ; National Natural Science Foundation of China[11171330] ; Key Laboratory of RCSDS, CAS[2008DP173182] ; BCMIIS
WOS研究方向Mathematics
语种英语
WOS记录号WOS:000396792600004
出版者SPRINGER
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/25213]  
专题应用数学研究所
通讯作者Sun, Liuquan
作者单位1.Wuhan Univ, Sch Math & Stat, Wuhan 430072, Hubei, Peoples R China
2.Chinese Acad Sci, Inst Appl Math, Acad Math & Syst Sci, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714		 Ding, Jieli,Sun, Liuquan. Additive mixed effect model for recurrent gap time data[J]. LIFETIME DATA ANALYSIS,2017,23(2):223-253.
APA Ding, Jieli,&Sun, Liuquan.(2017).Additive mixed effect model for recurrent gap time data.LIFETIME DATA ANALYSIS,23(2),223-253.
MLA Ding, Jieli,et al."Additive mixed effect model for recurrent gap time data".LIFETIME DATA ANALYSIS 23.2(2017):223-253.

入库方式： OAI收割

来源：数学与系统科学研究院

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。