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Joint modeling of recurrent and terminal events using additive models

文献类型：期刊论文

作者Qu, Lianqiang1; Sun, Liuquan1; Liu, Lei2
刊名STATISTICS AND ITS INTERFACE
出版日期2017
卷号10期号:4页码:699-710
关键词Additive models Estimating equations Frailty Partial marginal models Recurrent events Terminal event
ISSN号1938-7989
英文摘要In this article, we propose a joint modeling approach for the analysis of recurrent event data with a terminal event. We specify an additive rates model with a multiplicative frailty for the conditional recurrent event rate, and an additive hazards frailty model for the terminal event. A shared frailty is used to account for the association between recurrent and terminal events. An estimating equation approach is developed for the marginal and association parameters in the joint model, and the asymptotic properties of the proposed estimators are established. The finite sample performance of the proposed estimators is examined through simulation studies, and an application to a medical cost study of chronic heart failure patients is illustrated.
资助项目National Natural Science Foundation of China[11231010] ; National Natural Science Foundation of China[11171330] ; Key Laboratory of RCSDS ; CAS[2008DP173182] ; BCMIIS ; Agency of Healthcare Research and Quality of USA[R01 HS 020263]
WOS研究方向Mathematical & Computational Biology ; Mathematics
语种英语
WOS记录号WOS:000402401300012
出版者INT PRESS BOSTON, INC
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/25692]  
专题应用数学研究所
通讯作者Sun, Liuquan
作者单位1.Chinese Acad Sci, Acad Math & Syst Sci, Inst Appl Math, Beijing 100190, Peoples R China
2.Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA
推荐引用方式
GB/T 7714		 Qu, Lianqiang,Sun, Liuquan,Liu, Lei. Joint modeling of recurrent and terminal events using additive models[J]. STATISTICS AND ITS INTERFACE,2017,10(4):699-710.
APA Qu, Lianqiang,Sun, Liuquan,&Liu, Lei.(2017).Joint modeling of recurrent and terminal events using additive models.STATISTICS AND ITS INTERFACE,10(4),699-710.
MLA Qu, Lianqiang,et al."Joint modeling of recurrent and terminal events using additive models".STATISTICS AND ITS INTERFACE 10.4(2017):699-710.

入库方式： OAI收割

来源：数学与系统科学研究院

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