A weighted rank-sum procedure for comparing samples with multiple endpoints
文献类型:期刊论文
作者 | Li, Qizhai1,2![]() |
刊名 | STATISTICS AND ITS INTERFACE
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出版日期 | 2009 |
卷号 | 2期号:2页码:197-201 |
关键词 | Asymptotic normality Behrens-Fisher problem Case-Control Clinical trials Multiple endpoints Rank-sum statistics Weights |
ISSN号 | 1938-7989 |
英文摘要 | For comparing the distribution of two samples with multiple endpoints, O'Brien (1984) proposed rank-sum-type test statistics. Huang et al. (2005) extended these statistics to the general nonparametric Behrens-Fisher hypothesis problem and obtained improved test statistics by replacing the ad hoc variance with the asymptotic variance of the rank-sum statistics. In this paper we generalize the work of O'Brien (1984) and Huang et al. (2005) and propose a weighted rank-sum statistic. We show that the weighted rank-sum statistic is asymptotically normally distributed, permitting the computation of power, p-values and confidence intervals. We further demonstrate via simulation that the weighted rank-sum statistic is efficient in controlling the type I error rate and under certain alternatives, is more powerful than the statistics of O'Brien (1984) and Huang et al. (2005). |
资助项目 | National Institutes of Health ; Chinese Academy of Sciences |
WOS研究方向 | Mathematical & Computational Biology ; Mathematics |
语种 | 英语 |
WOS记录号 | WOS:000282649700010 |
出版者 | INT PRESS BOSTON, INC |
源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/8667] ![]() |
专题 | 系统科学研究所 |
作者单位 | 1.NCI, Biostat Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA 2.Chinese Acad Sci, Acad Math & Syst Sci, Beijing 100864, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Qizhai,Liu, Aiyi,Yu, Kai,et al. A weighted rank-sum procedure for comparing samples with multiple endpoints[J]. STATISTICS AND ITS INTERFACE,2009,2(2):197-201. |
APA | Li, Qizhai,Liu, Aiyi,Yu, Kai,&Yu, Kai F..(2009).A weighted rank-sum procedure for comparing samples with multiple endpoints.STATISTICS AND ITS INTERFACE,2(2),197-201. |
MLA | Li, Qizhai,et al."A weighted rank-sum procedure for comparing samples with multiple endpoints".STATISTICS AND ITS INTERFACE 2.2(2009):197-201. |
入库方式: OAI收割
来源:数学与系统科学研究院
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