A Rank-Based Test for Comparison of Multidimensional Outcomes
文献类型：期刊论文
| 作者 | Liu, Aiyi1; Li, Qizhai2 ; Liu, Chunling1; Yu, Kai; Yu, Kai F.1,3
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| 刊名 | JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
 |
| 出版日期 | 2010-06-01 |
| 卷号 | 105期号:490页码:578-587 |
| 关键词 | Autism spectrum disorder Behrens-Fisher problem Cardioprotective solution Case-control studies Growth hormones Multiple outcomes Nonparametrics Rank-sum statistics |
| ISSN号 | 0162-1459 |
| DOI | 10.1198/jasa.2010.ap09114 |
| 英文摘要 | For comparison of multiple outcomes commonly encountered in biomedical research, Huang et al. (2005) improved O'Brien's (1984) rank-sum tests through the replacement of the ad hoc variance by the asymptotic variance of the test statistics. The improved tests control the type I error rate at the desired level and gain power when the differences between the two comparison groups in each outcome variable lie in the same direction; however, they may lose power when the differences are in different directions (e.g., some are positive and some are negative). These tests and the popular Bonferroni correction failed to show important significant differences when applied to compare heart rates from a clinical trial to evaluate the effect of a procedure to remove the cardioprotective solution HTK. We propose an alternative test statistic, taking the maximum of the individual rank-sum statistics, which controls the type I error rate and maintains satisfactory power regardless of the direction of the differences. Simulation studies show the proposed test to be of higher power than other tests in a certain alternative parameter space of interest. Furthermore, when used to analyze the heart rate data, the proposed test yields more satisfactory results. |
| 资助项目 | Eunice Kennedy Shriver National Institute of Child Health and Human Development ; National Cancer Institute ; National Young Science Foundation of China[10901155] |
| WOS研究方向 | Mathematics |
| 语种 | 英语 |
| WOS记录号 | WOS:000280216700011 |
| 出版者 | AMER STATISTICAL ASSOC |
| 源URL | [http://ir.amss.ac.cn/handle/2S8OKBNM/9353]  |
| 专题 | 系统科学研究所 |
| 通讯作者 | Liu, Aiyi |
| 作者单位 | 1.Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Rockville, MD 20852 USA 2.Chinese Acad Sci, Acad Math & Syst Sci, Key Lab Syst & Control, Beijing 100190, Peoples R China 3.Natl Canc Inst, Rockville, MD 20852 USA |
| 推荐引用方式 GB/T 7714 | Liu, Aiyi,Li, Qizhai,Liu, Chunling,et al. A Rank-Based Test for Comparison of Multidimensional Outcomes[J]. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION,2010,105(490):578-587. |
| APA | Liu, Aiyi,Li, Qizhai,Liu, Chunling,Yu, Kai,&Yu, Kai F..(2010).A Rank-Based Test for Comparison of Multidimensional Outcomes.JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION,105(490),578-587. |
| MLA | Liu, Aiyi,et al."A Rank-Based Test for Comparison of Multidimensional Outcomes".JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION 105.490(2010):578-587. |
入库方式： OAI收割
来源：数学与系统科学研究院
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