中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Dynamical analysis of fractional order model of immunogenic tumors

文献类型:期刊论文

作者Arshad, Sadia1,2; Baleanu, Dumitru3,4; Huang, Jianfei5; Tang, Yifa1; Al Qurashi, Maysaa Mohamed6
刊名ADVANCES IN MECHANICAL ENGINEERING
出版日期2016-07-01
卷号8期号:7页码:13
关键词Fractional differential equation immune-tumor model stability and bifurcation analysis numerical solutions
ISSN号1687-8140
DOI10.1177/1687814016656704
英文摘要In this article, we examine the fractional order model of the cytotoxic T lymphocyte response to a growing tumor cell population. We investigate the long-term behavior of tumor growth and explore the conditions of tumor elimination analytically. We establish the conditions for the tumor-free equilibrium and tumor-infection equilibrium to be asymptotically stable and provide the expression of the basic reproduction number. Existence of physical significant tumor-infection equilibrium points is investigated analytically. We show that tumor growth rate, source rate of immune cells, and death rate of immune cells play vital role in tumor dynamics and system undergoes saddle-node and transcritical bifurcation based on these parameters. Furthermore, the effect of cancer treatment is discussed by varying the values of relevant parameters. Numerical simulations are presented to illustrate the analytical results.
资助项目"Research Center of the Center for Female Scientific and Medical Colleges", Deanship of Scientific Research, King Saud University ; King Saud University
WOS研究方向Thermodynamics ; Engineering
语种英语
WOS记录号WOS:000385215200031
出版者SAGE PUBLICATIONS LTD
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/23949]  
专题计算数学与科学工程计算研究所
通讯作者Arshad, Sadia
作者单位1.Chinese Acad Sci, Acad Math & Syst Sci, ICMSEC, LSEC, Beijing 100190, Peoples R China
2.COMSATS Inst Informat Technol, Lahore, Pakistan
3.Cankaya Univ, Fac Arts & Sci, Dept Math, Ankara, Turkey
4.Inst Space Sci, Magurele, Romania
5.Qingdao Univ, Coll Math, Qingdao, Peoples R China
6.King Saud Univ, Dept Math, Riyadh, Saudi Arabia
推荐引用方式
GB/T 7714
Arshad, Sadia,Baleanu, Dumitru,Huang, Jianfei,et al. Dynamical analysis of fractional order model of immunogenic tumors[J]. ADVANCES IN MECHANICAL ENGINEERING,2016,8(7):13.
APA Arshad, Sadia,Baleanu, Dumitru,Huang, Jianfei,Tang, Yifa,&Al Qurashi, Maysaa Mohamed.(2016).Dynamical analysis of fractional order model of immunogenic tumors.ADVANCES IN MECHANICAL ENGINEERING,8(7),13.
MLA Arshad, Sadia,et al."Dynamical analysis of fractional order model of immunogenic tumors".ADVANCES IN MECHANICAL ENGINEERING 8.7(2016):13.

入库方式: OAI收割

来源:数学与系统科学研究院

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