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Two novel diterpenoids from Isodon rubescens var. lushanensis

文献类型：期刊论文

作者Zhang, Hai-Bo1,2; Du, Xue1; Pu, Jian-Xin1; Wang, Yuan-Yuan1; He, Fei1; Zhao, Yong1; Li, Xiao-Nian1; Luo, Xiao1; Xiao, Wei-Lie1; Li, Yan1
刊名TETRAHEDRON LETTERS
出版日期2010-08-11
卷号51期号:32页码:4225-4228
关键词Isodon Rubescens Var. Lushanensis Diterpenoid Luanchunin a Luanchunin b
ISSN号0040-4039
DOI10.1016/j.tetlet.2010.06.015
文献子类Article
英文摘要Two novel diterpenoids, luanchunins A (1) and B (2), along with their precursor, kamebakaurin (3), had been isolated from the stems and leaves of Isodon rubescens var. lushanensis. Their structures were elucidated on the basis of extensive spectroscopic analyses. Compounds 1 and 2 showed potent cytotoxic activity against HL-60 with IC(50) values of 4.81 mu M and 3.52 mu M, respectively. Plausible pathways for the biosynthesis of 1 and 2 were also postulated. (C) 2010 Elsevier Ltd. All rights reserved.
学科主题Chemistry ; Organic
WOS关键词ENT-KAURANE DITERPENOIDS ; ERIOCALYX ; SKELETON
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000280345800019
资助机构NSFC [30772637, 30830119]; NSFC-Joint Foundation of Yunnan Province [U0832602]; Major State Basic Research Development Program of China [2009CB522300, 2009CB940900]; Natural Science Foundation of Yunnan Province [2008CD162]; CAS [KSCX2-YW-R-25]
公开日期2011-11-24
源URL[http://ir.kib.ac.cn:8080/handle/151853/1499]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Hai-Bo,Du, Xue,Pu, Jian-Xin,et al. Two novel diterpenoids from Isodon rubescens var. lushanensis[J]. TETRAHEDRON LETTERS,2010,51(32):4225-4228.
APA Zhang, Hai-Bo.,Du, Xue.,Pu, Jian-Xin.,Wang, Yuan-Yuan.,He, Fei.,...&Sun, Han-Dong.(2010).Two novel diterpenoids from Isodon rubescens var. lushanensis.TETRAHEDRON LETTERS,51(32),4225-4228.
MLA Zhang, Hai-Bo,et al."Two novel diterpenoids from Isodon rubescens var. lushanensis".TETRAHEDRON LETTERS 51.32(2010):4225-4228.

入库方式： OAI收割

来源：昆明植物研究所

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