Two new quaternary alkaloids and anti-hepatitis B virus active constituents from Corydalis saxicola
文献类型：期刊论文
| 作者 | Wu, Ying-Rui; Ma, Yun-Bao; Zhao, You-Xing; Yao, Shu-Ying; Zhou, Jun ; Zhou, Ying; Chen, Ji-Jun
|
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2007-07-01 |
| 卷号 | 73期号:8页码:787-791 |
| 关键词 | Corydalis Saxicola Bunting Fumariaceae Quaternary Isoquinoline Alkaloids Anti-hbv Activity |
| ISSN号 | 0032-0943 |
| DOI | 10.1055/s-2007-981549 |
| 文献子类 | Article |
| 英文摘要 | Two new quaternary isoquinoline alkaloids, saxicolalines A (1) and N-methylnarceimicine (2), together with sixteen known alkaloids (3-18) were isolated from Corydalis saxicola Bunting. The structures of saxicolalines A (1) and N-methylnarceimicine (2) were established based on spectral methods including 1D, 2D NMR (COSY, HMQC, HMBC) and HR-ESI-MS. The anti-HBV activities of ten main alkaloids were evaluated. Among the tested compounds, dihydrochelerythrine (8) exhibited the most potent activity against HBsAg and HBeAg secretions with IC50 < 0.05 mu M, SI > 3.5, respectively. |
| 学科主题 | Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy |
| WOS关键词 | BENZOPHENANTHRIDINE ALKALOIDS |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000248437500013 |
| 公开日期 | 2011-11-24 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/1549]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China 3.Guangxi Inst Chinese Med & Pharmaceut Sci, Nanning, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Ying-Rui,Ma, Yun-Bao,Zhao, You-Xing,et al. Two new quaternary alkaloids and anti-hepatitis B virus active constituents from Corydalis saxicola[J]. PLANTA MEDICA,2007,73(8):787-791. |
| APA | Wu, Ying-Rui.,Ma, Yun-Bao.,Zhao, You-Xing.,Yao, Shu-Ying.,Zhou, Jun.,...&Chen, Ji-Jun.(2007).Two new quaternary alkaloids and anti-hepatitis B virus active constituents from Corydalis saxicola.PLANTA MEDICA,73(8),787-791. |
| MLA | Wu, Ying-Rui,et al."Two new quaternary alkaloids and anti-hepatitis B virus active constituents from Corydalis saxicola".PLANTA MEDICA 73.8(2007):787-791. |
入库方式： OAI收割
来源：昆明植物研究所
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