Norfriedelins A-C with Acetylcholinesterase Inhibitory Activity from Acerola Tree (Malpighia emarginata)
文献类型：期刊论文
| 作者 | Liu, Jie-Qing1; Peng, Xing-Rong1,2; Li, Xu-Yang1,2; Li, Ting-Zhao3; Zhang, Wei-Ming1,2 ; Shi, Lei1; Han, Jiang3; Qiu, Ming-Hua1,2
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2013-04-05 |
| 卷号 | 15期号:7页码:1580-1583 |
| ISSN号 | 1523-7060 |
| 关键词 | Lines In-vitro Friedelane Triterpenoids Cholinergic Hypothesis Secofriedelane Assignments Growth Fruit H-1 |
| 通讯作者 | Qiu, MH (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China. ; mhchiu@mail.kib.ac.cn |
| 文献子类 | Article |
| 英文摘要 | Three novel norfriedelanes, A-C (1-3), were isolated from the branches and roots of Malpighia emarginata. Their structures and absolute configurations were determined by 1D and 2D NMR techniques and X-ray crystallographic analysis. Norfriedelin A (possessing an alpha-oxo-beta-lactone group) and norfriedelin B (with a keto-lactone group) showed acetylcholinesterase inhibitory effects with the IC50 values of 10.3 and 28.7 mu m, respectively. |
| 学科主题 | Chemistry, Organic |
| WOS关键词 | LINES IN-VITRO ; FRIEDELANE TRITERPENOIDS ; CHOLINERGIC HYPOTHESIS ; ALZHEIMERS-DISEASE ; SECOFRIEDELANE ; ASSIGNMENTS ; THERAPY ; GROWTH ; FRUIT ; H-1 |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000317327900041 |
| 资助机构 | Amway RD project [RD20111027Z]; NSFC [81202437]; High-Tech Special Project of Yunnan Province [0703C51211]; CAS [Y0225211Y1]; Major Drug Discovery Project of MOST [2011ZX09307-002-02] |
| 公开日期 | 2013-07-24 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/16535]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Amway China Bot Res Ctr, Wuxi 214115, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Jie-Qing,Peng, Xing-Rong,Li, Xu-Yang,et al. Norfriedelins A-C with Acetylcholinesterase Inhibitory Activity from Acerola Tree (Malpighia emarginata)[J]. ORGANIC LETTERS,2013,15(7):1580-1583. |
| APA | Liu, Jie-Qing.,Peng, Xing-Rong.,Li, Xu-Yang.,Li, Ting-Zhao.,Zhang, Wei-Ming.,...&Qiu, Ming-Hua.(2013).Norfriedelins A-C with Acetylcholinesterase Inhibitory Activity from Acerola Tree (Malpighia emarginata).ORGANIC LETTERS,15(7),1580-1583. |
| MLA | Liu, Jie-Qing,et al."Norfriedelins A-C with Acetylcholinesterase Inhibitory Activity from Acerola Tree (Malpighia emarginata)".ORGANIC LETTERS 15.7(2013):1580-1583. |
入库方式： OAI收割
来源：昆明植物研究所
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