Bioactive Abietane and ent-Kaurane Diterpenoids from Isodon tenuifolius
文献类型：期刊论文
| 作者 | Yang, Jian-Hong1,2; Du, Xue1; He, Fei1; Zhang, Hai-Bo1; Li, Xiao-Nian1; Su, Jia1; Li, Yan1 ; Pu, Jian-Xin1; Sun, Han-Dong1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2013-02-01 |
| 卷号 | 76期号:2页码:256-264 |
| ISSN号 | 0163-3864 |
| 关键词 | Adenantha |
| 通讯作者 | Pu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China. ; pujianxin@mail.kib.ac.cn |
| 文献子类 | Article |
| 英文摘要 | Three new abietane diterpenoids, isoabietenins A-C (1-3), and 13 new ent-kauranoids, tenuifolins A-M (4-16), along with four known compounds (17-20), were isolated from the aerial parts of Isodon tenuifolius. The structures of the new metabolites were established on the basis of detailed spectroscopic analysis. The absolute configurations of 1, 15, and 16 were confirmed by single-crystal X-ray diffraction. Selected compounds were evaluated for their cytotoxicity against a small panel of human tumor cell lines, and some compounds showed inhibitory effects. Furthermore, several isolates exhibited inhibitory activity against nitric oxide production in LPS-activated RAW264.7 macrophages. |
| 学科主题 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| WOS关键词 | ADENANTHA |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000315431800018 |
| 资助机构 | NSFC-Joint Foundation of Yunnan Province [U0832602]; National Natural Science Foundation of China [81172939]; Major State Basic Research Development Program of China [2009CB522300]; Reservation-Talent Project of Yunnan Province [2011CI043]; Major Direction Projection Foundation of CAS Intellectual Innovation Project [KSCX2-EW-J-24] |
| 公开日期 | 2013-07-24 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/16543]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Jian-Hong,Du, Xue,He, Fei,et al. Bioactive Abietane and ent-Kaurane Diterpenoids from Isodon tenuifolius[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(2):256-264. |
| APA | Yang, Jian-Hong.,Du, Xue.,He, Fei.,Zhang, Hai-Bo.,Li, Xiao-Nian.,...&Sun, Han-Dong.(2013).Bioactive Abietane and ent-Kaurane Diterpenoids from Isodon tenuifolius.JOURNAL OF NATURAL PRODUCTS,76(2),256-264. |
| MLA | Yang, Jian-Hong,et al."Bioactive Abietane and ent-Kaurane Diterpenoids from Isodon tenuifolius".JOURNAL OF NATURAL PRODUCTS 76.2(2013):256-264. |
入库方式： OAI收割
来源：昆明植物研究所
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