中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Antibacterial lignans and triterpenoids from Rostellularia procumbens

文献类型:期刊论文

作者Yongli Zhang; Fukai Bao; Juanjuan Hu; Shengwang Liang; YuZhang; Guanhua Du; CaijunZhang; Yongxian Cheng
刊名PLANTA MEDICA
出版日期2007-12-01
卷号73期号:15页码:1596-1599
关键词Necrosis-factor-alpha Justicia-procumbens Arylnaphthalide Lignans Cytotoxic Lignans Macrophages Apoptosis Cells
ISSN号0032-0943
DOI10.1055/s-2007-993747
文献子类Article
英文摘要One new lignan, rostellulin A (1), four known lignans, justin B (2), justicidin C (3), cilinaphthalide A (4), and justicidin A (5), and four known triterpenoids, ursolic acid (6), euscaphic acid (7), 2 alpha-hydroxyursolic acid (8), and tormentic acid (9), have been isolated from the whole plants of Rostellularia procumbens. Their structures were established on the basis of spectral data, including extensive NMR experiments. To our knowledge, compounds 6-9 are known compounds but not previously isolated from R. procumbens, 4 was previously reported from other Rostellularia species. Antibacterial activities of 1-9 were evaluated against eight bacterial strains with the agar dilution method, and they were found to possess antimicrobial activity with MIC values in the range of 1.56-100 mu g/mL. None of the lignans exhibited cytotoxic activity against HCT-8 and Bel-7402 cells at concentrations up to 5 pg/mL.
学科主题Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy
WOS关键词NECROSIS-FACTOR-ALPHA ; JUSTICIA-PROCUMBENS ; ARYLNAPHTHALIDE LIGNANS ; CYTOTOXIC LIGNANS ; MACROPHAGES ; APOPTOSIS ; CELLS
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000252715400014
公开日期2011-11-24
源URL[http://ir.kib.ac.cn:8080/handle/151853/1965]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式
GB/T 7714
Yongli Zhang,Fukai Bao,Juanjuan Hu,et al. Antibacterial lignans and triterpenoids from Rostellularia procumbens[J]. PLANTA MEDICA,2007,73(15):1596-1599.
APA Yongli Zhang.,Fukai Bao.,Juanjuan Hu.,Shengwang Liang.,YuZhang.,...&Yongxian Cheng.(2007).Antibacterial lignans and triterpenoids from Rostellularia procumbens.PLANTA MEDICA,73(15),1596-1599.
MLA Yongli Zhang,et al."Antibacterial lignans and triterpenoids from Rostellularia procumbens".PLANTA MEDICA 73.15(2007):1596-1599.

入库方式: OAI收割

来源:昆明植物研究所

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