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New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum

文献类型：期刊论文

作者Ma, Juan; Zhao, Pei-Ji; Shen, Yue-Mao
刊名ARCHIVES OF PHARMACAL RESEARCH
出版日期2007-06-01
卷号30期号:6页码:670-673
关键词Actinosynnema Pretiosum Ansamitocin Ansamitocinoside Antineoplastic Activity
ISSN号0253-6269
文献子类Article
英文摘要By using preparative TLC as the critical isolation procedure, two compounds, including one new amide N-glycosides of ansamitocin (2), were isolated from Actinosynnema pretiosum. The compounds were elucidated as N-demethyl-N-beta-D-glucopyranosyl ansamitocin P-2, named ansamitocinoside P-2 (1), and N-demethyl-N-beta-D-glucopyranosyl ansamitocin P-1, named ansamitocinoside P-1 (2) on the basis of their spectral data. The H-1-NMR and C-13-NMR assignments were made for 1 and 2 while the C-13-NMR assignment for 1 was revised. Bioassay results showed that 1 had antineoplastic activity.
学科主题Chemistry ; Medicinal ; Pharmacology & Pharmacy
WOS关键词ANTITUMOR AGENT ANSAMITOCIN ; TUMOR INHIBITORS ; MAYTANSINOIDS ; P-3
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000248367900002
公开日期2011-11-24
源URL[http://ir.kib.ac.cn:8080/handle/151853/2039]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714		 Ma, Juan,Zhao, Pei-Ji,Shen, Yue-Mao. New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum[J]. ARCHIVES OF PHARMACAL RESEARCH,2007,30(6):670-673.
APA Ma, Juan,Zhao, Pei-Ji,&Shen, Yue-Mao.(2007).New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum.ARCHIVES OF PHARMACAL RESEARCH,30(6),670-673.
MLA Ma, Juan,et al."New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum".ARCHIVES OF PHARMACAL RESEARCH 30.6(2007):670-673.

入库方式： OAI收割

来源：昆明植物研究所

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