Vibralactone: A lipase inhibitor with an unusual fused beta-lactone produced by cultures of the basidiomycete Boreostereum vibrans
文献类型：期刊论文
| 作者 | Liu, Dong-Ze; Wang, Fei; Liao, Tou-Gen; Tang, Jian-Guo; Steglich, Wolfgang; Zhu, Hua-Jie; Liu, Ji-Kai |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2006-12-07 |
| 卷号 | 8期号:25页码:5749-5752 |
| 关键词 | Ab-initio Calculation Optical-rotation Microbial Metabolite Neuroblastoma-cells Stereum-purpureum Lactacystin Tetrahydrolipstatin Orlistat Catalyst Acid |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol062307u |
| 文献子类 | Article |
| 英文摘要 | The structure and absolute configuration of vibralactone (1) from the cultures of the Basidiomycete Boreostereum vibrans were established by spectroscopic methods and computational methods. Vibralactone, an unusual fused beta-lactone-type metabolite, was found to inhibit pancreatic lipase with an IC50 of 0.4 mu g/mL. |
| 学科主题 | Chemistry ; Organic |
| WOS关键词 | AB-INITIO CALCULATION ; OPTICAL-ROTATION ; MICROBIAL METABOLITE ; NEUROBLASTOMA-CELLS ; STEREUM-PURPUREUM ; LACTACYSTIN ; TETRAHYDROLIPSTATIN ; ORLISTAT ; CATALYST ; ACID |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000242405900018 |
| 公开日期 | 2011-11-24 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/2141]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Univ Munich, Dept Chem, D-81377 Munich, Germany |
| 推荐引用方式 GB/T 7714 | Liu, Dong-Ze,Wang, Fei,Liao, Tou-Gen,et al. Vibralactone: A lipase inhibitor with an unusual fused beta-lactone produced by cultures of the basidiomycete Boreostereum vibrans[J]. ORGANIC LETTERS,2006,8(25):5749-5752. |
| APA | Liu, Dong-Ze.,Wang, Fei.,Liao, Tou-Gen.,Tang, Jian-Guo.,Steglich, Wolfgang.,...&Liu, Ji-Kai.(2006).Vibralactone: A lipase inhibitor with an unusual fused beta-lactone produced by cultures of the basidiomycete Boreostereum vibrans.ORGANIC LETTERS,8(25),5749-5752. |
| MLA | Liu, Dong-Ze,et al."Vibralactone: A lipase inhibitor with an unusual fused beta-lactone produced by cultures of the basidiomycete Boreostereum vibrans".ORGANIC LETTERS 8.25(2006):5749-5752. |
入库方式： OAI收割
来源：昆明植物研究所
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