Abiesanordines A-N: fourteen new norditerpenes from Abies georgei
文献类型：期刊论文
| 作者 | Yang, Xian-Wen1; Li, Su-Mei2; Feng, Lin3; Shen, Yun-Heng1; Tian, Jun-Mian1; Liu, Xiao-Hua1; Zeng, Hua-Wu1; Zhang, Chuan1; Zhang, Wei-Dong1,4 |
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2008-05-05 |
| 卷号 | 64期号:19页码:4354-4362 |
| 关键词 | Abies Georgei Pinaceae Norditerpenoids Podocarpenes Abiesanordines A-n Nitric Oxide (No) Raw264.7 Macrophages |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2008.02.069 |
| 通讯作者 | zc100@citiz.net ; wdzhangy@hotmail.com |
| 文献子类 | Article |
| 英文摘要 | Fourteen new norditerpenoids (abiesanordines A-N, 1-14), including a novel podocarpene bearing a rare enolic structure (abiesanordine A, 1). were isolated from Abies georgei together with eight known ones. Their structures were determined mainly by detailed analysis of 1D and 2D NMR spectroscopic data including HSQC, DQF COSY, HMBC, and NOESY. All the isolates were tested for inhibitory activities against LPS-induced NO production in RAW264.7 macrophages, abiesanordine 1 (9) showed the strongest activity with the IC50 value of 17.0 mu g/mL. Furthermore, it exhibited no cytotoxicity against RAW264.7 macrophages under the concentration of 50 mu g/mL. (c) 2008 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry, Organic |
| WOS关键词 | LARIX-KAEMPFERI ; CONSTITUENTS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000255585600024 |
| 公开日期 | 2011-12-19 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/2935]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Second Mil Med Univ, Sch Pharm, Dept Nat Prod Chem, Shanghai 200433, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, Dept Ethnobot, Kunming 650204, Peoples R China 3.Jiangxi Univ Tradit Chinese Med, Dept Pharm, Nanchang 330004, Peoples R China 4.Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Xian-Wen,Li, Su-Mei,Feng, Lin,et al. Abiesanordines A-N: fourteen new norditerpenes from Abies georgei[J]. TETRAHEDRON,2008,64(19):4354-4362. |
| APA | Yang, Xian-Wen.,Li, Su-Mei.,Feng, Lin.,Shen, Yun-Heng.,Tian, Jun-Mian.,...&Zhang, Wei-Dong.(2008).Abiesanordines A-N: fourteen new norditerpenes from Abies georgei.TETRAHEDRON,64(19),4354-4362. |
| MLA | Yang, Xian-Wen,et al."Abiesanordines A-N: fourteen new norditerpenes from Abies georgei".TETRAHEDRON 64.19(2008):4354-4362. |
入库方式： OAI收割
来源：昆明植物研究所
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