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Chinese Academy of Sciences Institutional Repositories Grid
Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida

文献类型:期刊论文

作者Qiu, Minghua; Kim, Jung-Hee; Lee, Hyeong-Kyu; Min, Byung-Sun
刊名PHYTOTHERAPY RESEARCH
出版日期2006-11-01
卷号20期号:11页码:945-948
关键词Cimicifuga Foetida Cycloartane-type Triterpenoid Anticomplement Activity Cimilactone a
ISSN号0951-418X
DOI10.1002/ptr.1982
通讯作者bsmin@cu.ac.kr
文献子类Article
英文摘要A tetranor-cycloartane glycoside and two 9,19-cycloartane glycosides were isolated from the EtOAc-soluble fraction of the rhizome of Cimicifuga foetida. The structures of the compounds were determined to be cimilactone A (1), 25-O-acetylcimigenol 3-O-beta-D-xylopyranoside (2) and cimigenol 3-O-alpha-L-arabinopyranoside (3), respectively, using spectroscopic analysis. The three compounds were examined for their anticomplement activity against the classical pathway of the complement system. Compound 1 showed significant anticomplement activity with an IC50 value of 28.6 mu m, whereas compounds 2 and 3 were inactive. Copyright (c) 2006 John Wiley & Sons, Ltd.
学科主题Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS关键词ANTI-COMPLEMENT ACTIVITY ; TRITERPENE GLYCOSIDES ; SIMPLEX WORMSK ; IN-VITRO ; RACEMOSA ; CONSTITUENTS ; DAHURICA ; SAPONINS
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000242254000004
公开日期2011-12-19
源URL[http://ir.kib.ac.cn:8080/handle/151853/2971]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Catholic Univ Daegu, Coll Pharm, Gyeongbuk 712702, South Korea
2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Korea Res Inst Biosci & Biotechnol, Taejon 305333, South Korea
推荐引用方式
GB/T 7714
Qiu, Minghua,Kim, Jung-Hee,Lee, Hyeong-Kyu,et al. Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida[J]. PHYTOTHERAPY RESEARCH,2006,20(11):945-948.
APA Qiu, Minghua,Kim, Jung-Hee,Lee, Hyeong-Kyu,&Min, Byung-Sun.(2006).Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida.PHYTOTHERAPY RESEARCH,20(11),945-948.
MLA Qiu, Minghua,et al."Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida".PHYTOTHERAPY RESEARCH 20.11(2006):945-948.

入库方式: OAI收割

来源:昆明植物研究所

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