Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida
文献类型:期刊论文
| 作者 | Qiu, Minghua ; Kim, Jung-Hee; Lee, Hyeong-Kyu; Min, Byung-Sun
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| 刊名 | PHYTOTHERAPY RESEARCH
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| 出版日期 | 2006-11-01 |
| 卷号 | 20期号:11页码:945-948 |
| 关键词 | Cimicifuga Foetida Cycloartane-type Triterpenoid Anticomplement Activity Cimilactone a |
| ISSN号 | 0951-418X |
| DOI | 10.1002/ptr.1982 |
| 通讯作者 | bsmin@cu.ac.kr |
| 文献子类 | Article |
| 英文摘要 | A tetranor-cycloartane glycoside and two 9,19-cycloartane glycosides were isolated from the EtOAc-soluble fraction of the rhizome of Cimicifuga foetida. The structures of the compounds were determined to be cimilactone A (1), 25-O-acetylcimigenol 3-O-beta-D-xylopyranoside (2) and cimigenol 3-O-alpha-L-arabinopyranoside (3), respectively, using spectroscopic analysis. The three compounds were examined for their anticomplement activity against the classical pathway of the complement system. Compound 1 showed significant anticomplement activity with an IC50 value of 28.6 mu m, whereas compounds 2 and 3 were inactive. Copyright (c) 2006 John Wiley & Sons, Ltd. |
| 学科主题 | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| WOS关键词 | ANTI-COMPLEMENT ACTIVITY ; TRITERPENE GLYCOSIDES ; SIMPLEX WORMSK ; IN-VITRO ; RACEMOSA ; CONSTITUENTS ; DAHURICA ; SAPONINS |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000242254000004 |
| 公开日期 | 2011-12-19 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/2971] ![]() |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Catholic Univ Daegu, Coll Pharm, Gyeongbuk 712702, South Korea 2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Korea Res Inst Biosci & Biotechnol, Taejon 305333, South Korea |
| 推荐引用方式 GB/T 7714 | Qiu, Minghua,Kim, Jung-Hee,Lee, Hyeong-Kyu,et al. Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida[J]. PHYTOTHERAPY RESEARCH,2006,20(11):945-948. |
| APA | Qiu, Minghua,Kim, Jung-Hee,Lee, Hyeong-Kyu,&Min, Byung-Sun.(2006).Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida.PHYTOTHERAPY RESEARCH,20(11),945-948. |
| MLA | Qiu, Minghua,et al."Anticomplement activity of cycloartane glycosides from the rhizome of Cimicifuga foetida".PHYTOTHERAPY RESEARCH 20.11(2006):945-948. |
入库方式: OAI收割
来源:昆明植物研究所
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