Norlignans from Sequoia sempervirens
文献类型：期刊论文
| 作者 | Zhang, YM; Tan, NH; Yang, YB; Lu, Y; Cao, P; Wu, YS |
| 刊名 | CHEMISTRY & BIODIVERSITY
 |
| 出版日期 | 2005 |
| 卷号 | 2期号:4页码:497-505 |
| 关键词 | Taiwania-cryptomerioides |
| ISSN号 | 1612-1872 |
| 文献子类 | Article |
| 英文摘要 | Six new norlignans, named sequosempervirins B-G (1-6), together with three known norlignans, agatharesinol (7), agatharesinol acetonide (8), and sugiresinol (9), were isolated from the branches and leaves of Sequoia sempervirens. Their structures were determined mainly by high-resolution mass spectroscopy (HRMS), and various 1D- and 2D-NMR methods, as well as, in the case of 1, by means of X-ray diffraction. Compound 8 showed anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 mu m). The acetone extract of S. sempervirens was found to be antifungal towards Candida glabrata (IC50 = 15.98 mu g/ml), and both the acetone and MeOH extracts inhibited the proteolytic activity of cathepsin B (IC50 = 4.58 and 5.49 mu g/ml, resp.). |
| 学科主题 | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
| WOS关键词 | TAIWANIA-CRYPTOMERIOIDES |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000228770000008 |
| 公开日期 | 2012-03-21 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/4048]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China 4.Peking Union Med Coll, Beijing 100050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, YM,Tan, NH,Yang, YB,et al. Norlignans from Sequoia sempervirens[J]. CHEMISTRY & BIODIVERSITY,2005,2(4):497-505. |
| APA | Zhang, YM,Tan, NH,Yang, YB,Lu, Y,Cao, P,&Wu, YS.(2005).Norlignans from Sequoia sempervirens.CHEMISTRY & BIODIVERSITY,2(4),497-505. |
| MLA | Zhang, YM,et al."Norlignans from Sequoia sempervirens".CHEMISTRY & BIODIVERSITY 2.4(2005):497-505. |
入库方式： OAI收割
来源：昆明植物研究所
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