中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A formal asymmetric synthesis of calabar bean alkaloids

文献类型:期刊论文

作者Node, M; Hao, XJ; Nishide, K; Fuji, K
刊名CHEMICAL & PHARMACEUTICAL BULLETIN
出版日期1996-04-01
卷号44期号:4页码:715-719
关键词(-)-eserethole (-)-physostigmine Asymmetric Nitroolefination Diels-alder Reaction Nitro Group Aromatization
ISSN号0009-2363
文献子类Article
英文摘要A total synthesis of (-)-eserethole (2) has been accomplished using the Diels-Alder reaction of (S)-(-)-2-methyl-2- [Z-(E)-nitroethenyl]-delta-valerolactone (3) and Danishefsky's diene as a key step, The synthesis of optically pure (-)-eserethole (2) constitutes a formal synthesis of naturally occurring Calabar bean alkaloids, such as (-)-physostigmine (1), (-)-physovenine (17) and(-)-geneserine (18).
学科主题Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
WOS关键词ADDITION ELIMINATION PROCESS ; QUATERNARY CARBON CENTERS ; DIELS-ALDER REACTIONS ; UNNATURAL (+)-PHYSOSTIGMINE ; ANTICHOLINESTERASE ACTIVITY ; ENANTIOSELECTIVE SYNTHESIS ; PHYSOSTIGMINE ALKALOIDS ; CARBAMATE ANALOGS ; (-)-PHYSOSTIGMINE ; ROUTE
WOS研究方向Pharmacology & Pharmacy ; Chemistry
语种英语
WOS记录号WOS:A1996UG30100015
公开日期2012-03-21
源URL[http://ir.kib.ac.cn:8080/handle/151853/4068]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.ACAD SINICA, KUNMING INST BOT, KUNMING 650204, YUNNAN, PEOPLES R CHINA
2.KYOTO UNIV, CHEM RES INST, UJI, KYOTO 611, JAPAN
推荐引用方式
GB/T 7714
Node, M,Hao, XJ,Nishide, K,et al. A formal asymmetric synthesis of calabar bean alkaloids[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,1996,44(4):715-719.
APA Node, M,Hao, XJ,Nishide, K,&Fuji, K.(1996).A formal asymmetric synthesis of calabar bean alkaloids.CHEMICAL & PHARMACEUTICAL BULLETIN,44(4),715-719.
MLA Node, M,et al."A formal asymmetric synthesis of calabar bean alkaloids".CHEMICAL & PHARMACEUTICAL BULLETIN 44.4(1996):715-719.

入库方式: OAI收割

来源:昆明植物研究所

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