A formal asymmetric synthesis of calabar bean alkaloids
文献类型：期刊论文
| 作者 | Node, M; Hao, XJ ; Nishide, K; Fuji, K
|
| 刊名 | CHEMICAL & PHARMACEUTICAL BULLETIN
 |
| 出版日期 | 1996-04-01 |
| 卷号 | 44期号:4页码:715-719 |
| 关键词 | (-)-eserethole (-)-physostigmine Asymmetric Nitroolefination Diels-alder Reaction Nitro Group Aromatization |
| ISSN号 | 0009-2363 |
| 文献子类 | Article |
| 英文摘要 | A total synthesis of (-)-eserethole (2) has been accomplished using the Diels-Alder reaction of (S)-(-)-2-methyl-2- [Z-(E)-nitroethenyl]-delta-valerolactone (3) and Danishefsky's diene as a key step, The synthesis of optically pure (-)-eserethole (2) constitutes a formal synthesis of naturally occurring Calabar bean alkaloids, such as (-)-physostigmine (1), (-)-physovenine (17) and(-)-geneserine (18). |
| 学科主题 | Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy |
| WOS关键词 | ADDITION ELIMINATION PROCESS ; QUATERNARY CARBON CENTERS ; DIELS-ALDER REACTIONS ; UNNATURAL (+)-PHYSOSTIGMINE ; ANTICHOLINESTERASE ACTIVITY ; ENANTIOSELECTIVE SYNTHESIS ; PHYSOSTIGMINE ALKALOIDS ; CARBAMATE ANALOGS ; (-)-PHYSOSTIGMINE ; ROUTE |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:A1996UG30100015 |
| 公开日期 | 2012-03-21 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/4068]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.ACAD SINICA, KUNMING INST BOT, KUNMING 650204, YUNNAN, PEOPLES R CHINA 2.KYOTO UNIV, CHEM RES INST, UJI, KYOTO 611, JAPAN |
| 推荐引用方式 GB/T 7714 | Node, M,Hao, XJ,Nishide, K,et al. A formal asymmetric synthesis of calabar bean alkaloids[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,1996,44(4):715-719. |
| APA | Node, M,Hao, XJ,Nishide, K,&Fuji, K.(1996).A formal asymmetric synthesis of calabar bean alkaloids.CHEMICAL & PHARMACEUTICAL BULLETIN,44(4),715-719. |
| MLA | Node, M,et al."A formal asymmetric synthesis of calabar bean alkaloids".CHEMICAL & PHARMACEUTICAL BULLETIN 44.4(1996):715-719. |
入库方式： OAI收割
来源：昆明植物研究所
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