Cytotoxic isoprenylated xanthones from Cudrania tricuspidata
文献类型：期刊论文
| 作者 | Zou, YS; Hou, AJ; Zhu, GF; Chen, YF; Sun, HD ; Zhao, QS
|
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY
 |
| 出版日期 | 2004-04-15 |
| 卷号 | 12期号:8页码:1947-1953 |
| ISSN号 | 0968-0896 |
| 关键词 | Root Bark Prenylated Xanthones Moraceae Plants Maclura-pomifera Components Constituents Cochinchinensis Flavones Wood |
| DOI | 10.1016/j.bmc.2004.01.030 |
| 文献子类 | Article |
| 英文摘要 | Eight new isoprenylated xanthones, cudratricusxanthones A-H (1-8), were isolated from the roots of Cudrania tricuspidata, together with ten known compounds, cudraxanthones H (9) and M (10), xanthone V,a (11), toxyloxanthone C (12), macluraxanthone B (13), 1-hydroxy-3, 6, 7-trimethoxyxanthone (14), cycloartocarpesin (15), artocarpesin (16), cudraflavone B (17), and kaempferol (18). Their structures were characterized by spectroscopic methods. Xanthones 5, 7, 10, and 12 showed inhibitory effects on four kinds of human digestive apparatus tumor cell lines (HCT-116, SMMC-7721, SGC-7901, and BGC-823) with IC50 values of 1.6-11.8 mug/mL. Xanthones 2, 4, and 11 displayed significant cytotoxicity against HCT-116, SMMC-7721, and SGC-7901 (IC50 = 1.3-9.8 mug/mL). Flavonoids 15-17 were almost inactive. (C) 2004 Elsevier Ltd. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology ; Chemistry, Medicinal ; Chemistry, Organic |
| WOS关键词 | ROOT BARK ; PRENYLATED XANTHONES ; MORACEAE PLANTS ; MACLURA-POMIFERA ; COMPONENTS ; CONSTITUENTS ; COCHINCHINENSIS ; FLAVONES ; WOOD |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000220754600012 |
| 公开日期 | 2012-03-21 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/4148]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Fudan Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 200032, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Sch Chinese Pharm, Shanghai 201203, Peoples R China 3.Acad Sinica, Kunming Inst Bot, Lab Phytochem, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zou, YS,Hou, AJ,Zhu, GF,et al. Cytotoxic isoprenylated xanthones from Cudrania tricuspidata[J]. BIOORGANIC & MEDICINAL CHEMISTRY,2004,12(8):1947-1953. |
| APA | Zou, YS,Hou, AJ,Zhu, GF,Chen, YF,Sun, HD,&Zhao, QS.(2004).Cytotoxic isoprenylated xanthones from Cudrania tricuspidata.BIOORGANIC & MEDICINAL CHEMISTRY,12(8),1947-1953. |
| MLA | Zou, YS,et al."Cytotoxic isoprenylated xanthones from Cudrania tricuspidata".BIOORGANIC & MEDICINAL CHEMISTRY 12.8(2004):1947-1953. |
入库方式： OAI收割
来源：昆明植物研究所
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