Maoecrystal V, cytotoxic diterpenoid with a novel C-19 skeleton from Isodon eriocalyx (Dunn.) Hara
文献类型：期刊论文
| 作者 | Li, SH ; Wang, J; Niu, XM; Shen, YH; Zhang, HJ; Sun, HD; Li, ML; Tian, QE; Lu, Y; Cao, P
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2004-11-11 |
| 卷号 | 6期号:23页码:4327-4330 |
| 关键词 | Ent-kaurane Diterpenoids Var. Laxiflora Rubescens Crystal Dimer |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol0481535 |
| 文献子类 | Article |
| 英文摘要 | Maoecrystal V (1), a novel C-19 diterpenoid possessing a unique 6,7-seco-6-nor-15(8-->9)-abeo-5,8-epoxy-ent-kaurane skeleton, was isolated from the leaves of a Chinese medicinal herb, Isodon eriocalyx. Its structure was determined by comprehensive NMR and MS spectroscopic analysis and confirmed by single-crystal X-ray diffraction study. Compound 1 showed remarkable inhibitory activity toward HeLa cells with IC50 = 0.02 mug/mL (cis-platin: IC50 = 0.99 mug/mL). |
| 学科主题 | Chemistry, Organic |
| WOS关键词 | ENT-KAURANE DITERPENOIDS ; VAR. LAXIFLORA ; RUBESCENS ; CRYSTAL ; DIMER |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000224973100049 |
| 公开日期 | 2012-03-21 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/4252]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 2.Kunming Med Coll, Yunnan Pharmacol Lab Nat Prod, Kunming 650031, Yunnan, Peoples R China 3.Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, SH,Wang, J,Niu, XM,et al. Maoecrystal V, cytotoxic diterpenoid with a novel C-19 skeleton from Isodon eriocalyx (Dunn.) Hara[J]. ORGANIC LETTERS,2004,6(23):4327-4330. |
| APA | Li, SH.,Wang, J.,Niu, XM.,Shen, YH.,Zhang, HJ.,...&Zheng, QT.(2004).Maoecrystal V, cytotoxic diterpenoid with a novel C-19 skeleton from Isodon eriocalyx (Dunn.) Hara.ORGANIC LETTERS,6(23),4327-4330. |
| MLA | Li, SH,et al."Maoecrystal V, cytotoxic diterpenoid with a novel C-19 skeleton from Isodon eriocalyx (Dunn.) Hara".ORGANIC LETTERS 6.23(2004):4327-4330. |
入库方式： OAI收割
来源：昆明植物研究所
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