Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii
文献类型：期刊论文
| 作者 | Tong, Xiao-Gang2,3; Zhou, Li-Li1; Wang, Yue-Hu2 ; Xia, Chengfeng2; Wang, Ye4,5; Liang, Min; Hou, Fan-Fan1; Cheng, Yong-Xian2
|
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2010-04-16 |
| 卷号 | 12期号:8页码:1844-1847 |
| 关键词 | High-glucose Mesangial Cells Expression Inhibitors Activation Products Oxidase Acid |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol100451p |
| 文献子类 | Article |
| 英文摘要 | Acortatarins A (1) and B (2), two novel spiroalkaloids with a naturally unusual morpholine motif, were isolated from the rhizome of Acorus tatarinowii. Their structures with absolute configuration were determined by spectroscopic methods, X-ray diffraction analysis, and Masher's method. Importantly, compound 1 could significantly inhibit reactive oxygen species production in high-glucose-stimulated mesangial cells in a dose- and time-dependent manner. |
| 学科主题 | Chemistry, Organic |
| WOS关键词 | HIGH-GLUCOSE ; MESANGIAL CELLS ; EXPRESSION ; INHIBITORS ; ACTIVATION ; PRODUCTS ; OXIDASE ; ACID |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000276562600050 |
| 资助机构 | Chinese Academy of Sciences (CAS) [KSCX2-YW-R-118, KSCX2-YW-R-211]; Yunnan Youth [2007PY01-48]; Kunming Institute of Botany [P2008-ZZ11]; National Natural Science Foundation [30830056] |
| 公开日期 | 2012-03-21 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/4282]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.So Med Univ, Div Nephrol, Nanfang Hosp, Key Lab Organ Failure Res,Educ Minist, Guangzhou 510515, Guangdong, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 4.Chinese Acad Sci, Guiyang 550002, Guizhou, Peoples R China 5.Key Lab Chem Nat Prod Guizhou Prov, Guiyang 550002, Guizhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tong, Xiao-Gang,Zhou, Li-Li,Wang, Yue-Hu,et al. Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii[J]. ORGANIC LETTERS,2010,12(8):1844-1847. |
| APA | Tong, Xiao-Gang.,Zhou, Li-Li.,Wang, Yue-Hu.,Xia, Chengfeng.,Wang, Ye.,...&Cheng, Yong-Xian.(2010).Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii.ORGANIC LETTERS,12(8),1844-1847. |
| MLA | Tong, Xiao-Gang,et al."Acortatarins A and B, Two Novel Antioxidative Spiroalkaloids with a Naturally Unusual Morpholine Motif from Acorus tatarinowii".ORGANIC LETTERS 12.8(2010):1844-1847. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。