Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata
文献类型：期刊论文
| 作者 | Zhang, HJ; Fan, ZT; Tan, GT; Chai, HB; Pezzuto, JM; Sun, HD ; Fong, HHS
|
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2002-02-01 |
| 卷号 | 65期号:2页码:215-217 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/np010420h |
| 通讯作者 | Sun, HD, Acad Sinica, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China |
| 文献子类 | Article |
| 英文摘要 | A new ent-kaurene diterpene, pseudoirroratin A (1), and a known diterpene, pseurata A, were isolated from Isodon pseudo-irrorata. Compound 1 showed significant cytotoxicity against the Lu1, SW626, LNCaP, KB, and HOS cancer cell, lines with IC50 values of 0.26 (0.75), 0.20 (0.57), 0.90 (2.59), 0.90 (2.59), and 0.50 (1.44) mug/mL (muM), respectively. The structure of 1 was elucidated by spectroscopic means including 1D and 2D NMR techniques. |
| 学科主题 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| WOS关键词 | RABDOSIA |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000174048900024 |
| 公开日期 | 2012-03-21 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/4582]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Acad Sinica, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 2.Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA 3.Xizang Plateau Inst Biol, Lasa 850001, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, HJ,Fan, ZT,Tan, GT,et al. Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata[J]. JOURNAL OF NATURAL PRODUCTS,2002,65(2):215-217. |
| APA | Zhang, HJ.,Fan, ZT.,Tan, GT.,Chai, HB.,Pezzuto, JM.,...&Fong, HHS.(2002).Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata.JOURNAL OF NATURAL PRODUCTS,65(2),215-217. |
| MLA | Zhang, HJ,et al."Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata".JOURNAL OF NATURAL PRODUCTS 65.2(2002):215-217. |
入库方式： OAI收割
来源：昆明植物研究所
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