Cytotoxic 3,20-Epoxy-ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora
文献类型：期刊论文
| 作者 | Niu, XM; Li, SH ; Mei, SX; Na, Z; Zhao, QS; Lin, ZW; Sun, HD
|
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2002-12-01 |
| 卷号 | 65期号:12页码:1892-1896 |
| 关键词 | Heracleum Rapula Coumarin Glucosides Furanocoumarin Bicoumarin Angelica-archangelica Coumarins Glucosides |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/np020059e |
| 文献子类 | Article |
| 英文摘要 | Four new ent-kaurane diterpenoids, laxiflorins J-M (1-4), along with maoecrystal A (5) and maoecrystal P (6), were isolated from the leaves of Isodon eriocalyx var. laxiflora. Their structures were determined by spectroscopic analyses. All the compounds were assayed for their cytotoxic effects on human tumor K562, A549, and T24 cell lines. Compounds 1 and 6 showed significant inhibitory effects on human tumor K562 and T24 cells, with IC50 values less than 0.5 mug/mL. Compound 3 also demonstrated cytotoxic activities against all three types of human tumor cells, with IC50 values in the range of 1-25 mug/mL. |
| 学科主题 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000180190100028 |
| 公开日期 | 2012-03-21 |
| 源URL | [http://ir.kib.ac.cn:8080/handle/151853/4590]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Niu, XM,Li, SH,Mei, SX,et al. Cytotoxic 3,20-Epoxy-ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora[J]. JOURNAL OF NATURAL PRODUCTS,2002,65(12):1892-1896. |
| APA | Niu, XM.,Li, SH.,Mei, SX.,Na, Z.,Zhao, QS.,...&Sun, HD.(2002).Cytotoxic 3,20-Epoxy-ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora.JOURNAL OF NATURAL PRODUCTS,65(12),1892-1896. |
| MLA | Niu, XM,et al."Cytotoxic 3,20-Epoxy-ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora".JOURNAL OF NATURAL PRODUCTS 65.12(2002):1892-1896. |
入库方式： OAI收割
来源：昆明植物研究所
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