A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner
文献类型:期刊论文
作者 | Rinner, Beate2; Kretschmer, Nadine1; Knausz, Heike2; Mayer, Andrea2; Boechzelt, Herbert3; Hao, Xiao-Jiang4![]() |
刊名 | JOURNAL OF ETHNOPHARMACOLOGY
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出版日期 | 2010-05-27 |
卷号 | 129期号:2页码:182-188 |
关键词 | Onosma Paniculatum Zicao Cancer Cell Cycle Caspase-3 |
ISSN号 | 0378-8741 |
DOI | 10.1016/j.jep.2010.02.006 |
通讯作者 | Bauer, R, Karl Franzens Univ Graz, Dept Pharmacognosy, Inst Pharmaceut Sci, Univ Pl 4, A-8010 Graz, Austria |
文献子类 | Article |
英文摘要 | Aim of the study: Traditional Chinese medicine (TCM) has become very popular in Western countries during the last years. Zicao, a remedy of TCM, has been traditionally used to treat cancer, and, its main constituents, naphthoquinones, have been reported to possess antitumor activity (Chen et al., 2002; Papageorgiou et al., 1999). Here, we prepared extracts of different polarities of Onosma paniculatum Bur. & Franch., a plant which is amongst others used as Zicao, but, much less investigated. The extracts were analyzed concerning their growth inhibitory and apoptosis-inducing activity in various tumor cells. |
学科主题 | Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy |
WOS关键词 | TRADITIONAL CHINESE MEDICINE ; NAPHTHOQUINONE DERIVATIVES ; INDUCED APOPTOSIS ; NATURAL-PRODUCTS ; CANCER-THERAPY ; IN-VITRO ; SHIKONIN ; DNA ; PHARMACOGENOMICS ; INDUCTION |
WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine |
语种 | 英语 |
WOS记录号 | WOS:000278651300005 |
资助机构 | Fonds zur Foerderung der Wissenschaftlichen Forschung [P21114] |
公开日期 | 2012-03-21 |
源URL | [http://ir.kib.ac.cn:8080/handle/151853/4916] ![]() |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Karl Franzens Univ Graz, Dept Pharmacognosy, Inst Pharmaceut Sci, A-8010 Graz, Austria 2.Med Univ Graz, Core Facil Flow Cytometry, Med Res Ctr, A-8010 Graz, Austria 3.Joanneum Res Forsch Gesell mbH, A-8010 Graz, Austria 4.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 5.LMU Dept Biol Systemat Bot & Mykol, D-80638 Munich, Germany 6.Johannes Gutenberg Univ Mainz, Dept Pharmaceut Biol, Inst Pharm, D-55099 Mainz, Germany 7.Med Univ Graz, Dept Dermatol, Canc Biol Unit, A-8036 Graz, Austria 8.Med Univ Graz, Med Res Ctr, A-8036 Graz, Austria |
推荐引用方式 GB/T 7714 | Rinner, Beate,Kretschmer, Nadine,Knausz, Heike,et al. A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner[J]. JOURNAL OF ETHNOPHARMACOLOGY,2010,129(2):182-188. |
APA | Rinner, Beate.,Kretschmer, Nadine.,Knausz, Heike.,Mayer, Andrea.,Boechzelt, Herbert.,...&Bauer, Rudolf.(2010).A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner.JOURNAL OF ETHNOPHARMACOLOGY,129(2),182-188. |
MLA | Rinner, Beate,et al."A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner".JOURNAL OF ETHNOPHARMACOLOGY 129.2(2010):182-188. |
入库方式: OAI收割
来源:昆明植物研究所
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