中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Bioactive flavones and biflavones from Selaginella moellendorffii Hieron

文献类型:期刊论文

作者Cao, Yuan1; Tan, Nin-Hua3; Chen, Ji-Jun3; Zeng, Guang-Zhi3; Ma, Yun-Bao3; Wu, Yong-Ping2; Yan, He3; Yang, Jie1; Lu, Lai-Feng1; Wang, Qiang1
刊名FITOTERAPIA
出版日期2010-06-01
卷号81期号:4页码:253-258
关键词Selaginella Moellendorffii Selaginellacea Flavone Biflavone Anti-hbv Activity Cytotoxicity
ISSN号0367-326X
DOI10.1016/j.fitote.2009.09.007
文献子类Article
英文摘要Three new flavones named 5-carboxymethyl-4',7-dihydroxyflavone (1), its ethyl ester (2) and butyl ester (3) were isolated from the herb Selaginella moellendorffii Hieron., together with ten known compounds. Their structures were elucidated on the basis of spectroscopic and chemical analysis. Selected compounds were evaluated for their anti-HBV and cytotoxic activity. Among them, compounds 2 and 3 displayed inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the Hep G2.2.15 cell line with IC(50) values of 0.17 mg/ml and 0.46 mg/ml, and on HBV e antigen (HBeAg) secretion with IC(50) values of 0.42 mg/ml and 0.42 mg/ml, respectively. Compounds 7.8. 10 and 12 exhibited selective cytotoxicity against the three human cancer cell lines tested. (C) 2009 Elsevier By. All rights reserved.
学科主题Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS关键词CYTOTOXIC BIFLAVONOIDS ; DOEDERLEINII ; DELICATULA
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000277699400006
公开日期2012-03-21
源URL[http://ir.kib.ac.cn:8080/handle/151853/4974]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.China Pharmaceut Univ, Dept Chinese Mat Med Anal, Nanjing 210009, Peoples R China
2.Jiangsu Prov Inst Mat Med, Nanjing 210009, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
推荐引用方式
GB/T 7714
Cao, Yuan,Tan, Nin-Hua,Chen, Ji-Jun,et al. Bioactive flavones and biflavones from Selaginella moellendorffii Hieron[J]. FITOTERAPIA,2010,81(4):253-258.
APA Cao, Yuan.,Tan, Nin-Hua.,Chen, Ji-Jun.,Zeng, Guang-Zhi.,Ma, Yun-Bao.,...&Wang, Qiang.(2010).Bioactive flavones and biflavones from Selaginella moellendorffii Hieron.FITOTERAPIA,81(4),253-258.
MLA Cao, Yuan,et al."Bioactive flavones and biflavones from Selaginella moellendorffii Hieron".FITOTERAPIA 81.4(2010):253-258.

入库方式: OAI收割

来源:昆明植物研究所

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