Zhengyia shennongensis is described here as a new genus and species of the nettle family (Urticaceae) from Hubei province, central China. The phylogenetic position of Z. shennongensis is determined using DNA sequences of nuclear ribosomal ITS and three plastid regions (rbcL, psbA-trnH, trnL-F). Zhengyia shennongensis is readily distinguished from the related genera Urtica, Hesperocnide, and Laportea in the tribe Urticeae by its seed (oblong-globose or subglobose and not compressed achenes, surface densely covered with nipple-shaped protuberances) and stipule morphology (large leaf-like stipules with auriculate and amplexicaulous base and united with stem). Phylogenetic evidence indicates that Zhengyia is a distinct group related to Urtica (including Hesperocnide) species and Laportea cuspidata in tribe Urticeae. The bulbiliferous species of the tribe (L. bulbifera, L. cztspidata, Z. shennongensis) do not form a clade. This result indicates that the bulbil trait evolved in parallel within Urticeae. Our findings highlight the importance of shady and moist habitats in promoting species diversification and the parallel evolution of morphological traits that are likely to be adaptive.