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New pregnane saponins from Ecdysanthera rosea and their cytotoxicity

文献类型：期刊论文

作者Zhu, Xiangdong1,2; Wu, Guisheng1; Xiang, Jianying3; Luo, Huairong1; Luo, Shide1; Zhu, Hongmei4; Wang, Yifen1
刊名FITOTERAPIA
出版日期2011-06-01
卷号82期号:4页码:632-636
关键词Ecdysanthera Rosea Pregnane Saponin Ecdysantheroside b Cytotoxicity
ISSN号0367-326X
DOI10.1016/j.fitote.2011.01.022
通讯作者xdzhu815@yahoo.com.cn ; wangyifen@mail.kib.ac.cn
文献子类Article
英文摘要Two new pregnane saponins elucidated as ecdysantheroside A (1) and ecdysantheroside B (2) and six known compounds (3-8) based on spectral data (MS, IR, 1D and 2D NMR) were isolated from the stem bark of Ecdysanthera rosea. The cytotoxicity against six cell lines of these compounds was tested by MTT assay. The results revealed that compounds 5 and 7 showed cytotoxicity against all the cell lines. Compound 2 showed cytotoxicity against cells A549, MDA435, HepG2, and HUVEC, while compound 4 showed cytotoxicity against cells A549, CEM, and HUVEC. Compound 6 had cytotoxicity against the others except cell HepG2. (C) 2011 Elsevier B.V. All rights reserved.
学科主题Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS关键词GLYCOSIDES ; TRITERPENE
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000291140800018
资助机构National Natural Science Foundation[30860037, 20872148]; Department of Science and Technology in Yunnan Province[20080A007]
公开日期2012-03-16
源URL[http://ir.kib.ac.cn:8080/handle/151853/3940]  
专题昆明植物研究所_中国科学院东亚植物多样性与生物地理学重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
2.Jiangxi Agr Univ, Coll Biosci & Bioengn, Nanchang 330045, Peoples R China
3.Chinese Acad Sci, Key Lab Biodivers & Biogeog, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China
4.Xiamen Univ, Coll Oceanog & Environm Sci, Xiamen 361000, Peoples R China
推荐引用方式
GB/T 7714		 Zhu, Xiangdong,Wu, Guisheng,Xiang, Jianying,et al. New pregnane saponins from Ecdysanthera rosea and their cytotoxicity[J]. FITOTERAPIA,2011,82(4):632-636.
APA Zhu, Xiangdong.,Wu, Guisheng.,Xiang, Jianying.,Luo, Huairong.,Luo, Shide.,...&Wang, Yifen.(2011).New pregnane saponins from Ecdysanthera rosea and their cytotoxicity.FITOTERAPIA,82(4),632-636.
MLA Zhu, Xiangdong,et al."New pregnane saponins from Ecdysanthera rosea and their cytotoxicity".FITOTERAPIA 82.4(2011):632-636.

入库方式： OAI收割

来源：昆明植物研究所

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