中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer

文献类型:期刊论文

作者Ma, Liang1,2; Wen, Zhe-Sheng3; Liu, Zi1; Hu, Zheng4; Ma, Jun3; Chen, Xiao-Qin3; Liu, Yong-Qiang1; Pu, Jian-Xin5; Xiao, Wei-Lie5; Sun, Han-Dong5
刊名PLOS ONE
出版日期2011-05-31
卷号6期号:5页码:e20159
关键词Gastric-cancer Breast-cancer Phospho-akt Smoking Cells Carcinoma Survival Leukemia China
ISSN号1932-6203
DOI10.1371/journal.pone.0020159
通讯作者hdsun@mail.kib.ac.cn ; gbzhou@ioz.ac.cn
文献子类Article
英文摘要Background: Lung cancer is the leading cause of cancer deaths worldwide, with a five-year overall survival rate of only 15%. Cancerous inhibitor of PP2A (CIP2A) is a human oncoprotein inhibiting PP2A in many human malignancies. However, whether CIP2A can be a new drug target for lung cancer is largely unclear.
学科主题Biology
WOS关键词GASTRIC-CANCER ; BREAST-CANCER ; PHOSPHO-AKT ; SMOKING ; CELLS ; CARCINOMA ; SURVIVAL ; LEUKEMIA ; CHINA
WOS研究方向Science & Technology - Other Topics
语种英语
WOS记录号WOS:000291097600025
资助机构National Key Program for Basic Research (973)[2010CB529201]; Chinese Academy of Sciences[KSCX1-YW-R-26, KSCX2-YW-R-235]; National Natural Science Foundation of China[81071930, 30871110]; National Major Scientific and Technological Program for Drug Discovery[2009ZX09103-101]; Science and Technology Planning Project of Guangzhou[2009Y-C011-2]
公开日期2012-03-16
源URL[http://ir.kib.ac.cn:8080/handle/151853/3968]  
专题昆明植物研究所_中国科学院东亚植物多样性与生物地理学重点实验室
作者单位1.Chinese Acad Sci, Inst Zool, State Key Lab Biomembrane & Membrane Biotechnol, Div Mol Carcinogenesis & Targeted Therapy Canc, Beijing, Peoples R China
2.Univ Sci & Technol China, Sch Life Sci, Hefei 230026, Peoples R China
3.Sun Yat Sen Univ, Canc Hosp, Guangzhou 510275, Guangdong, Peoples R China
4.Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou, Guangdong, Peoples R China
5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Peoples R China
推荐引用方式
GB/T 7714
Ma, Liang,Wen, Zhe-Sheng,Liu, Zi,et al. Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer[J]. PLOS ONE,2011,6(5):e20159.
APA Ma, Liang.,Wen, Zhe-Sheng.,Liu, Zi.,Hu, Zheng.,Ma, Jun.,...&Zhou, Guang-Biao.(2011).Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer.PLOS ONE,6(5),e20159.
MLA Ma, Liang,et al."Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer".PLOS ONE 6.5(2011):e20159.

入库方式: OAI收割

来源:昆明植物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。