Y Pocahemiketals A and B, two new hemiketals with unprecedented sesquiterpenoid skeletons from Pogostemon cablin
文献类型：期刊论文
| 作者 | Zhu, Huan1,2; Zhou, Qin-Mei1,2; Peng, Cheng1,2; Chen, Ming-Hua3,4; Li, Xiao-Nian5; Lin, Da-Sheng6; Xiong, Liang1,2 |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2017-07-01 |
| 卷号 | 120页码:67-71 |
| ISSN号 | 0367-326X |
| 关键词 | Pogostemon Cablin Sesquiterpenoids Hemiketals Vasorelaxant Activity |
| DOI | 10.1016/j.fitote.2017.05.013 |
| 英文摘要 | Pocahemiketals A and B (1 and 2), two novel hemiketal sesquiterpenoids with unprecedented skeletons, were isolated from the essential oil of the aerial parts of Pogostemon cablin. In addition to a bicyclo[3.2.1]-carbon core, 1 and 2 possessed a hemiketal alpha,beta-unsaturated-gamma-lactone moiety. Their structures were determined by extensive spectroscopic analysis, electronic circular dichroism calculation, and single-crystal X-ray diffraction. Compound 2 exhibited significant vasorelaxant activity against phenylephrine-induced contraction of a rat aorta ring with the EC50 value of 16.32 mu M. |
| 学科主题 | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000407404000009 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/54945]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chengdu Univ Tradit Chinese Med, Sch Pharm, Chengdu 611137, Sichuan, Peoples R China 2.Chengdu Univ Tradit Chinese Med, State Key Lab Breeding Base Systemat Res Dev & Ut, Chengdu 611137, Sichuan, Peoples R China 3.Chinese Acad Med Sci, Inst Med Biotechnol, Beijing 100050, Peoples R China 4.Peking Union Med Coll, Beijing 100050, Peoples R China 5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 6.Chengdu Huasun Grp Co Ltd, Chengdu 610075, Sichuan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Huan,Zhou, Qin-Mei,Peng, Cheng,et al. Y Pocahemiketals A and B, two new hemiketals with unprecedented sesquiterpenoid skeletons from Pogostemon cablin[J]. FITOTERAPIA,2017,120:67-71. |
| APA | Zhu, Huan.,Zhou, Qin-Mei.,Peng, Cheng.,Chen, Ming-Hua.,Li, Xiao-Nian.,...&Xiong, Liang.(2017).Y Pocahemiketals A and B, two new hemiketals with unprecedented sesquiterpenoid skeletons from Pogostemon cablin.FITOTERAPIA,120,67-71. |
| MLA | Zhu, Huan,et al."Y Pocahemiketals A and B, two new hemiketals with unprecedented sesquiterpenoid skeletons from Pogostemon cablin".FITOTERAPIA 120(2017):67-71. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。